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Cytoprotective effect of silybin against lasalocid-induced toxicity in HepG2 cells [PDF]
, 2013 Lasalocid is an ionophore coccidiostatic agent frequently used in poultry. Its extensive use causes the formation of residues in edible tissues and eggs which may pose a risk to consumers. Silybin is the main compound extracted from the herb milk thistle
Cybulski, W., Rzeski, W., Radko, L.
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Alterations In Mitochondrial Ca2+ Flux By The Antibiotic X-537a (lasalocid-a).
, 2015 A previous communication (Pereira da Silva, L., Bernardes, C.F. and Vercesi, A.E. (1984) Biochem. Biophys. Res. Commun. 124, 80-86) presented evidence that lasalocid-A, at concentrations far below those required to act as a Ca2+ ionophore, significantly ...
Antonio, R V +2 more
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Spectroscopic, structural and antimicrobial investigation of new salts of lasalocid acid with amines
, 2013 Wydział ChemiiCelem pracy była synteza, ustalenie struktury oraz właściwości biologicznych nowych soli kwasu lasalowego z aminami, a także określenie konkurencji amin i kationów metali w kompleksowaniu przez kwas lasalowy.
Rutkowski, Jacek
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Synthesis of Lasalocid-Based Bioconjugates and Evaluation of Their Anticancer Activity
ACS Omega, 2022 Michał Antoszczak +4 more
doaj +1 more source
Aggregation of lasalocid A in membranes: a fluorescence study
Biochimica Et Biophysica Acta - Biomembranes, 1992 The aggregation behavior of the carboxylic ionophore, lasalocid A, has been studied in egg phosphatidylcholine vesicles by monitoring the intrinsic fluorescence of lasalocid A. Self quenching of lasalocid A fluorescence in vesicles of egg phosphatidylcholine suggests aggregation of lasalocid A.
Sneha Sudha Komath +2 more
exaly +4 more sources
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Development of an ELISA for lasalocid and depletion kinetics of lasalocid residues in poultry
Food Additives and Contaminants, 1995Polyclonal antibodies against the coccidiostat, lasalocid, were raised in sheep. The antisera were applied in an enzyme-linked immunosorbent assay (ELISA) for lasalocid, which was validated for chicken serum, liver and muscle. Bridge homology in the ELISA was overcome by absorbing unspecific antisera onto a conjugate between salinomycin and chicken ...
W John Blanchflower +2 more
exaly +3 more sources
Effect of Lasalocid on Fall-Calving Beef Cows
Journal of Animal Science, 1986 The effects of lasalocid on fall-calving beef cows were examined in a 196-d trial that began October 12, 1983. Forty-two crossbred cow-calf pairs were stratified to six groups by breed, calving date and sex of calf. Three replications of each of two treatments, 0 and 200 mg lasalocid X head-1 X d-1, were used. The cows were fed a combination of haylage
B, Hopman, D W, Weber
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Toxic Effects of Lasalocid in Horses
American Journal of Veterinary Research, 1981SUMMARY Lasalocid was given to horses in a series of sequentially increasing single oral doses ranging between 5 and 30 mg/kg of body weight, with an appropriate washout period between treatments. One of 5 horses died after a dosage of 15 mg/kg, 1 of 3 horses died after 21 mg/kg, 1 of 3 horses died after 22 mg/kg, and 1 of 2 horses died after 26 mg/kg.
L J, Hanson, H G, Eisenbeis, S V, Givens
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