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Biomedicine and Pharmacotherapy, 2017 Lasalocid is an antibiotic from the group of carboxylic ionophores, produced by Streptomyces lasaliensis. But there was limited information of lasalocid on human prostate cancer cells.
Kwang-Youn Kim +2 more
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Spectrofluorometric Determination of the Antibiotic Lasalocid in Blood
Journal of Pharmaceutical Sciences, 1975A spectrofluorometric assay was developed for the determination of the antibiotic lasalocid in dog blood, based on the intrinsic fluorescence of the compound in ethyl acetate. The assay can measure "total" levels of drug and any metabolites present. The specificity of the assay was verified by TLC separation of the dog blood extract, which indicated ...
M A, Brooks +4 more
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Acta Crystallographica Section C Crystal Structure Communications, 1995
The structures of two new forms of lasalocid sodium salt, sodium 6-[7R-{5S-ethyl-5-(5R-ethyltetrahydro-5-hydroxy-6S-methyl-2H-pyran-2R-yl)tetrahydro-3S-methyl-2S-furanyl}-4S-hydroxy-3R,5S-dimethyl-6-oxononyl]-2-hydroxy-3-methylbenzoate (A), Na + .C 34 H 53 O 8 − , and sodium 6-[7R-{5S-ethyl-5-(5R-ethyltetrahydro-5-hydroxy-6S-methyl-2H-pyran-2R-yl ...
X. Shui, D. S. Eggleston
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The structures of two new forms of lasalocid sodium salt, sodium 6-[7R-{5S-ethyl-5-(5R-ethyltetrahydro-5-hydroxy-6S-methyl-2H-pyran-2R-yl)tetrahydro-3S-methyl-2S-furanyl}-4S-hydroxy-3R,5S-dimethyl-6-oxononyl]-2-hydroxy-3-methylbenzoate (A), Na + .C 34 H 53 O 8 − , and sodium 6-[7R-{5S-ethyl-5-(5R-ethyltetrahydro-5-hydroxy-6S-methyl-2H-pyran-2R-yl ...
X. Shui, D. S. Eggleston
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Safety of lasalocid in turkeys and its compatibility with tiamulin
Veterinary Record, 1988An investigation involving 640 turkeys demonstrated that the inclusion of lasalocid continuously from day-old to 16 weeks of age, at levels up to 375 ppm in the feed, produced no adverse effects; furthermore, the inclusion of 125 ppm lasalocid in the feed was compatible with the administration of 250 ppm tiamulin in the drinking water continuously for ...
N J, Lodge +3 more
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Potassium and Lasalocid Effects on Performance and Digestion in Lambs
Journal of Animal Science, 1986Two trials were conducted to evaluate effects of dietary potassium (K) concentration and lasalocid (L) in lamb finishing diets. Treatments were arranged in a 2 X 2 factorial and consisted of a 65% concentrate diet with 1.1% K (C), .9% K + 21.3 mg L/kg (CL), 2.1% K (P) and 2.5% K + 20 mg L/kg (PL).
M A, Funk, M L, Galyean, T T, Ross
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Performance of beef heifers supplemented with sodium lasalocid
Tropical Animal Health and Production, 2016This study was conducted on 78 13-month-old crossbred beef heifers that weighed 215 kg in Southern Rio Grande do Sul (RS) State, Brazil. We evaluated the performance of beef heifers that were reared in a pasture system that received a mineral supplement energy-type protein with added sodium lasalocid (LAS).
Everton Dezordi, Sartori +5 more
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Fitness of Amines for Pseudocyclic Conformation of Lasalocid A
Journal of Biomolecular Structure and Dynamics, 1995Ionophore lasalocid A selectively transports amines across lipid membranes. The structures of amine-lasalocid complexes were calculated by a molecular mechanics technique. Four typical catecholamines were considered: serotonin, dopamine, noradrenaline and adrenaline.
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Evaluation of Lasalocid in Salt Against Ovine Coccidia
American Journal of Veterinary Research, 1981SUMMARY Lasalocid at a level of 0.75% in free-choice granulated salt was highly efficacious against naturally acquired coccidia infections in lambs maintained in semiconfinement. Treated lambs consumed 18 g of medicated salt/day, reflecting an average daily lasalocid dosage of 4.3 mg/kg of body weight.
W J, Foreyt, N L, Gates, J E, Rich
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Effect of lasalocid, monensin and thiopeptin on rumen protozoa
Research in Veterinary Science, 1986The effects of lasalocid, monensin and thiopeptin on the total number and the generic composition of rumen protozoa were determined in vivo and in vitro. Feeding lasalocid or monensin to cattle on either high grain or high roughage diets reduced total protozoal counts.
S M, Dennis, T G, Nagaraja, A D, Dayton
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The Total Synthesis of Lasalocid A
1980A total asymmetric synthesis of the "right half ketone" of the stereo-complex polyether antibiotic, lasalocid A, is described. The [3,3] sigmatropic rearrangements of 0-silylketene acetals derived from esters of 1,4-anhydro-pent-1-enitols (furanoid glycals) and 1,5-anhydro-hex-1-enitols (pyranoid glycals) provided α-substituted-2,5-dihydrofuran-2 ...
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