Results 41 to 50 of about 208,806 (265)

Laser intensity and incidence angle dependent attosecond light pulse generation from relativistic laser plasma surfaces

, 2022
Relativistic high-order harmonics from a few-cycle laser driven plasma surface is a very promising source of anintense and isolated attosecond light pulse. The laser to harmonics conversion efficiency and the “purity” ofan isolated attosecond light pulse
Veisz, Laszlo,, He, Jin, Chen, Jingbiao, Veisz, Laszlo, Ma, Guangjin   +4 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Synchronized off-harmonic probe laser with highly variable pulse duration for laser–plasma interaction experiments

High Power Laser Science and Engineering
This paper presents the development and experimental utilization of a synchronized off-harmonic laser system designed as a probe for ultra-intense laser–plasma interaction experiments.
J. Hornung, Y. Zobus, H. Lorenté, C. Brabetz, B. Zielbauer, V. Bagnoud   +5 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Laser-plasma interaction physics for shock ignition

EPJ Web of Conferences, 2013
In the shock ignition scheme, the ICF target is first compressed with a long (nanosecond) pulse before creating a convergent shock with a short (∼100 ps) pulse to ignite thermonuclear reactions.
Goyon C., Depierreux S., Michel D.T., Loisel G., Yahia V., Masson-Laborde P.E., Loiseau P., Hüller S., Borisenko N.G., Orekhov A., Rosmej O., Nicolaï P., Tikhonchuk V.T., Labaune C.   +13 more
doaj   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Optical probing of ultrafast laser-induced solid-to-overdense-plasma transitions

Light: Science & Applications
Understanding the solid target dynamics resulting from the interaction with an ultrashort laser pulse is a challenging fundamental multi-physics problem involving atomic and solid-state physics, plasma physics, and laser physics. Knowledge of the initial
Yasmina Azamoum, Georg Alexander Becker, Sebastian Keppler, Guillaume Duchateau, Stefan Skupin, Mickael Grech, Fabrice Catoire, Sebastian Hell, Issa Tamer, Marco Hornung, Marco Hellwing, Alexander Kessler, Franck Schorcht, Malte Christoph Kaluza   +13 more
doaj   +1 more source

Heat transfer properties of laser assisted plasma processing [PDF]

, 2012
Laser assisted plasma processing (LAPP) is a novel extension to already established Reactive Atom Plasma (RAP) processing for atmospheric pressure dry chemical etching of silicon based materials; this is mainly applied for optical uses.
Parkins, Jonathon
core  

Single shot, temporally and spatially resolved measurements of fast electron dynamics using a chirped optical probe

, 2014
A new approach to rear surface optical probing is presented that permits multiple, time-resolved 2D measurements to be made during a single, ultra-intense ( > 1018 W cm−2) laser-plasma interaction.
Booth, Nicola, Dance, Rachel, McKenna, Paul, Rusby, Dean, MacLellan, David, Green, J., Wilson, Lucy, Murphy, C.D., Gray, Ross   +8 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source