Results 101 to 110 of about 327,567 (274)

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

Advanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang, Hui‐Wen Liu, Hyogeun Shin, Hyun Wook Kang, Minjin Kang, Jongbaeg Kim, Il‐Joo Cho, Nakwon Choi, Seok Chung, Hong Nam Kim   +9 more
wiley   +1 more source

Efficient guiding and focusing of intense laser pulse using periodic thin slits

Matter and Radiation at Extremes
Slits have been widely used in laser–plasma interactions as plasma optical components for generating high-harmonic light and controlling laser-driven particle beams. Here, we propose and demonstrate that periodic thin slits can be regarded as a new breed
L. Xu, T. W. Huang, K. Jiang, C. N. Wu, H. Peng, P. Chen, R. Li, H. B. Zhuo, C. T. Zhou   +8 more
doaj   +1 more source

Unraveling the Mg Loss Mechanism and Degradation Kinetics in Thermoelectric n‐Type Mg2Si‐Mg2Sn Solid Solutions

Advanced Functional Materials, EarlyView.
Mg‐based thermoelectrics are among the most promising candidates for power generation applications but their performance is compromised by Mg loss at device operation temperatures due to the higher chemical potential of Mg (μMg${\mu}_{\mathrm{Mg}}$) inside the material compared to the environment.
Aryan Sankhla, Eckhard Mueller, Johannes de Boor   +2 more
wiley   +1 more source

Impact of extended preplasma on energy coupling in kilojoule energy relativistic laser interaction with cone wire targets relevant to fast ignition

New Journal of Physics, 2013
Cone-guided fast ignition laser fusion depends critically on details of the interaction of an intense laser pulse with the inside tip of a cone. Generation of relativistic electrons in the laser plasma interaction (LPI) with a gold cone and their ...
T Yabuuchi, R Mishra, C McGuffey, B Qiao, M S Wei, H Sawada, Y Sentoku, T Ma, D P Higginson, K U Akli, D Batani, H Chen, L A Gizzi, M H Key, A J Mackinnon, H S McLean, P A Norreys, P K Patel, R B Stephens, Y Ping, W Theobald, C Stoeckl, F N Beg   +22 more
doaj   +1 more source

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

Advanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo, Nguyen Thi Nguyen, LiLi Guo, Ngoc Man Phan, Hyunsu Shin, Tae‐il Kim, Yu Seok Youn, Jaeyun Kim   +7 more
wiley   +1 more source

Real-time bremsstrahlung detector as a monitoring tool for laser–plasma proton acceleration

High Power Laser Science and Engineering
Real-time evaluation of laser-driven byproducts is crucial for state-of-the-art facilities operating at high repetition rates. This work presents real-time measurements of hard X-rays (bremsstrahlung radiation) generated from the interaction of high ...
Valeria Istokskaia, Benoit Lefebvre, Roberto Versaci, Dragana B. Dreghici, Domenico Doria, Filip Grepl, Veronika Olšovcová, Francesco Schillaci, Stanislav Stanček, Maksym Tryus, Andriy Velyhan, Daniele Margarone, Lorenzo Giuffrida   +12 more
doaj   +1 more source

Effect of the Laser Wave Front in a Laser-Plasma Accelerator

Physical Review X, 2015
A high-repetition rate electron source is generated by tightly focusing kHz, few-mJ laser pulses into an underdense plasma. This high-intensity laser-plasma interaction leads to stable electron beams over several hours but with strikingly complex ...
B. Beaurepaire, A. Vernier, M. Bocoum, F. Böhle, A. Jullien, J-P. Rousseau, T. Lefrou, D. Douillet, G. Iaquaniello, R. Lopez-Martens, A. Lifschitz, J. Faure   +11 more
doaj   +1 more source

An All‐Optical Driven Bio‐Photovoltaic Interface for Active Control of Live Cells

Advanced Functional Materials, EarlyView.
Bio‐photovoltaic Interface (BIO‐PV‐I) for live cell manipulation is presented. BIO‐PV‐I can be activated non‐invasively and remotely to control the spatial motility, adhesion, and morphology of cells adhering to it. BIO‐PV‐I uses a patterned light‐induced electric potential in iron‐doped lithium niobate crystals whose light‐driven and reversible nature,
Lisa Miccio, Martina Mugnano, Valentina Marchesano, Alejandro Calabuig, Zhe Wang, Gennaro Giordano, Francesca Borrelli, Simonetta Grilli, Pietro Ferraro   +8 more
wiley   +1 more source

Efficiency of radiation friction losses in laser-driven ‘hole boring’ of dense targets

New Journal of Physics, 2019
In the interaction of laser pulses of extreme intensity (>10 ^23 Wcm ^−2 ) with high-density, thick plasma targets, simulations show significant radiation friction losses, in contrast to thin targets for which such losses are negligible.
S V Popruzhenko, T V Liseykina, A Macchi
doaj   +1 more source

Generating Cell Surface Nucleated Hydrogels with an Artificial Membrane‐Binding Transglutaminase

Advanced Functional Materials, EarlyView.
Cell‐based therapies require advanced strategies to enhance cell delivery and bioactivity. Cell membrane engineering offers an avenue to impart new functions to delivered cells to boost their viability and function. Here, an artificial membrane‐binding transglutaminase is generated and biophysically characterized.
Rosalia Cuahtecontzi Delint, Tao Li, Kapil D. Patel, Will H. Zhang, Ben M. Carter, Graham J. Day, Adam W. Perriman   +6 more
wiley   +1 more source