Results 101 to 110 of about 116,508 (264)

Stable and tunable MeV $$\gamma$$ -ray generation via dual-laser inverse Thomson scattering from a laser-plasma accelerator

Scientific Reports
Inverse Thomson scattering from laser-plasma accelerators offers a pathway to compact, tunable MeV $$\gamma$$ -ray sources for reduced-dose radiography and enhanced performance in nuclear resonance fluorescence (NRF)-based isotope identification. However,
Hai-En Tsai, Tobias M. Ostermayr, Robert E. Jacob, Qiang Chen, Benjamin J. Greenwood, Robert Ettelbrick, Anthony J. Gonsalves, Kei Nakamura, Liona Fan-Chiang, Ocean Zhou, Sam K. Barber, Fumika Isono, Scott J. Thompson, James T. Johnson, Jay D. Hix, Edward Seabury, David L. Chichester, Carl B. Schroeder, Eric Esarey, Jeroen van Tilborg, Cameron G. R. Geddes   +20 more
doaj   +1 more source

Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma

Advanced Healthcare Materials, EarlyView.
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett, Yann S. Vanrobaeys, Tessy Teboh, Zakiya Smith, Anderson Scott, Cynthia Hajal, Paula T. Hammond, Joelle P. Straehla   +7 more
wiley   +1 more source

Conjugated Porphyrin Polymer With Superior Charge Transfer for Photodynamic‐Immunomodulatory Prevention of CIED Infection in Diabetes

Advanced Healthcare Materials, EarlyView.
Under NIR irradiation, PTCPP generates ROS to eliminate MRSA biofilms and promote M1 macrophage polarization for phagocytosis. After bacterial clearance, the material is phagocytosed by macrophages, shifting their polarization to M2 phenotype via metabolic reprogramming, which synergistically enhances anti‐infection therapy and wound healing.
Honghao Ma, Jinguo Xu, Rongrong Gu, Chuanhui Dong, Te Chen, Yi Mu, Jing Zhu, Yating Wang, Wen Wang, Yingying Zhang, Hongyu Ma, Xiaochen Wang, Sheng Ye, Cheng Cheng   +13 more
wiley   +1 more source

Production and magnetic self-confinement of e−e+ plasma by an extremely intense laser pulse incident on a structured solid target

Matter and Radiation at Extremes
We propose an all-optical, single-laser-pulse scheme for generating a dense relativistic strongly magnetized electron–positron pair plasma. The scheme involves the interaction of an extremely intense (I ≳ 1024 W/cm2) circularly polarized laser pulse with
Alexander Samsonov, Alexander Pukhov
doaj   +1 more source

A Naphthalimide‐Based NIR‐Emissive AIE Photosensitizer for Synergistic Apoptosis/Ferroptosis‐Mediated Antitumor Therapy and Broad‐Spectrum Bacterial Inactivation With Rapid Wound Healing

Advanced Healthcare Materials, EarlyView.
An ionic naphthalimide AIE photosensitizer (PS), TPAPV‐NIM‐M, anchors to cellular and bacterial membranes, emits in the far‐red/near‐infrared (NIR) region, and efficiently generates reactive oxygen species (ROS) under white light. Its membrane‐localized photodynamic action drives apoptosis/ferroptosis‐mediated tumor suppression and broad‐spectrum ...
Sayed Mir Sayed, Zeeshan Tahir, Fahri Alkan, Yavuz Nuri Ertas   +3 more
wiley   +1 more source

Patterned ELR‐Gelatin Hydrogels Enable Rapid Endothelial Monolayer Formation via Bioactive Matrix Chemistry and Surface Topography

Advanced Healthcare Materials, EarlyView.
Micro‐ and nano‐patterned elastin‐like recombinamer (ELR) hydrogels integrate bioactive matrix chemistry with defined surface topography. The combined cues promote rapid endothelial cell capture, alignment, and monolayer formation on soft substrates.
Jagoda Litowczenko, Yannick Richter, Martyna Michalska, Piotr Paczos, Karine Tadevosyan, Daniel Uribe, Jose Carlos Rodriguez‐Cabello, Ioannis Papakonstantinou, Angel Raya   +8 more
wiley   +1 more source

Electromagnetic Burst Generation during Annihilation of Magnetic Field in Relativistic Laser-Plasma Interaction. [PDF]

Sci Rep, 2019
Gu YJ, Pegoraro F, Sasorov PV, Golovin D, Yogo A, Korn G, Bulanov SV.   +6 more
europepmc   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Global scattered-light spectrography for laser absorption and laser–plasma instability studies

High Power Laser Science and Engineering
An optical spectrometer system based on 60 channels of fibers has been designed and employed to diagnose light emissions from laser–plasma interactions. The 60 fiber collectors cover an integrated solid angle of $\pi$ , enabling the measurement of ...
Yihang Zhang, Zhe Zhang, Xu Zhao, Kevin Glize, Yufeng Dong, Xiaohui Yuan, Yutong Li, Jie Zhang   +7 more
doaj   +1 more source

Brilliant petawatt gamma-ray pulse generation in quantum electrodynamic laser-plasma interaction. [PDF]

Sci Rep, 2017
Chang HX, Qiao B, Huang TW, Xu Z, Zhou CT, Gu YQ, Yan XQ, Zepf M, He XT.   +8 more
europepmc   +1 more source