Results 41 to 50 of about 117,276 (312)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

WDM laser transmitters for mobile free-space laser communications [PDF]

, 2018
We describe the performance of versatile high-performance multi-rate WDM laser transmitters using next-generation compact high-extinction-ratio power-efficient (CHERPe) transmitter designs.
Schulein, Robert T., Stevens, Mark L., Spector, Steven Jay, Carney, John J., Caplan, David O.   +4 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Transformation of DLR's laser communication terminals for CubeSats towards new application scenarios [PDF]

Modern solutions for secure, robust and high-speed satellite communication rely on free-space optical communication in addition to classical radio-frequency channels.
Rödiger, Benjamin, Schmidt, Christopher, Rodeck, Lukas Rupert, Hahn, Marie-Theres   +3 more
core   +1 more source

A Balanced Dual-Intracavity Dual-Mode Interlocking Method for Fiber Laser Self-Reference Wavelength Stabilization

IEEE Photonics Journal
The laser frequency stabilization technology is very important in the development of laser applications, and the improvement of this technology has tend to further expectations for portability and low cost, in addition to the realization of strict ...
Liuxin Zhang, Kang Ying, Guochao Wang, Haoyang Pi, Zhaoyong Wang, Yanguang Sun, Fang Wei, Youzhen Gui, Qing Ye, Haiwen Cai   +9 more
doaj   +1 more source

Recent Progress in Distributed Fiber Acoustic Sensing with Φ-OTDR

Sensors, 2020
Distributed fiber acoustic sensing (DAS) technology can continuously spatially detect disturbances along the sensing fiber over long distance in real time.
Zhaoyong Wang, Bin Lu, Qing Ye, Haiwen Cai   +3 more
doaj   +1 more source

A Low Temperature Coefficient Time-to-Digital Converter with 1.3 ps Resolution Implemented in a 28 nm FPGA

Sensors, 2022
Time-to-digital converter (TDC) is the key technology to realize accurate time delay measurement in high-precision optical fiber time-frequency transmission and synchronization, optical sensing and many scientific applications.
Xiangyu Mao, Fei Yang, Fang Wei, Jiawen Shi, Jian Cai, Haiwen Cai   +5 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Optical Free-Space Communication on Earth and in Space regarding Quantum Cryptography Aspects

, 2010
Mobile FSO Communication links have gained signi cant at- tention over the last years due to their increasing maturity. They are used in point to point link scenarios where the high gain in power efficiency and datarate is crucial, compared to state-of ...
Fuchs, Christian, Giggenbach, Dirk, Christian Fuchs, Dirk Giggenbach   +3 more
core   +1 more source