Results 31 to 40 of about 66,021 (260)

SOFTWARE TOOL FOR LASER CUTTING PROCESS CONTROL – SOLVING REAL INDUSTRIAL CASE STUDIES

Facta Universitatis. Series: Mechanical Engineering, 2016
Laser cutting is one of the leading non-conventional machining technologies with a wide spectrum of application in modern industry. It order to exploit a number of advantages that this technology offers for contour cutting of materials, it is necessary ...
Miloš Madić, Marko Kovačević, Miroslav Radovanović, Vladislav Blagojević   +3 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

ANALYSIS OF THE EFFECT ON THE MECHANICAL PROPERTIES OF THE LASER CUTTING AIRCRAFT SKIN

Jixie qiangdu, 2015
Laser cutting technology is widely used in manufacturing industry. But the laser absorptivity of the aircraft skin material is low,and the laser cutting quality is poor,so laser cutting is not applied in manufacturing of the aircraft skin.
PENG YuHai, HOU HongLing, ZHANG Hui, XIE YuKun, PENG Kai   +4 more
doaj  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

LASER CUTTING OF SOFT STEEL IN INDUSTRIAL PARTS MANUFACTURING [PDF]

Analele Universităţii "Constantin Brâncuşi" din Târgu Jiu: Seria Inginerie, 2019
An interesting study on the cutting of flexible steel using the CO2 laser is discussed in this paper. We used a rigorous mathematical model resulting from the experiments performed to determine the cutting speed, the deviation from the circularity of the
Constantin Cristinel Gîrdu , Mircea Viorel Drăgoi , Mihaela Mileșan , Constanța Rădulescu   +3 more
doaj  

Laser Cutting Characteristics on Uncompressed Anode for Lithium-Ion Batteries

Energies, 2020
Lithium-ion batteries are actively used for many applications due to many advantages. Although electrodes are important during laser cutting, most laser cutting studies use commercially available electrodes. Thus, effects of electrodes characteristics on
Dongkyoung Lee, Jungdon Suk
doaj   +1 more source