Results 41 to 50 of about 164,526 (254)
Compact LWFA-Based Extreme Ultraviolet Free Electron Laser: Design Constraints
Instruments, 2022 The combination of advanced high-power laser technology, new acceleration methods and achievements in undulator development offers the opportunity to build compact, high-brilliance free electron lasers driven by a laser wakefield accelerator.
Alexander Yu. Molodozhentsev +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Advanced ScienceDue to its outstanding performance, laser display technology has received extensive attention. Specifically, in this study, a novel narrow‐band green phosphor, Na0.6Rb0.4BaB9O15 (NRBBO): Eu2+, for laser display is obtained.
Runtian Kang +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Polychromatic display of thermochromic liquid crystals enabled by near-infrared laser scanning
AIP AdvancesThis paper presents a polychromatic display (PD) utilizing thermochromic liquid crystals (TLCs) that exhibit temperature-dependent color changes operated via near-infrared (NIR) laser scanning.
Jonguk Yang, Sanghyun Ju
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Laser Display Technologies and Their Applications
The Journal of The Institute of Electrical Engineers of Japan, 2011 Abstract Laser displays have been attractive because extremely wide color expression can be realized by choosing the wavelength of laser sources. The high efficiency and small etendue of laser sources contribute to downsizing, and a long lifetime is also another merit for users.
openaire +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source