Bioprinted Stiffness‑Tunable Pancreatic Microniches to Decode Early Tumor Initiation Mechanisms
Advanced Healthcare Materials, EarlyView.Stiffness‐tunable GelMA microniches generated by microvalve bioprinting preserve wild‐type acinar identity while revealing a nonlinear, Kras‐dependent response to matrix mechanics. Intermediate stiffness promotes acinar‐to‐ductal metaplasia and proliferation, defining a permissive mechanical window.
Aurelien Mazet +11 more
wiley +1 more source
A Comparative Evaluation of Visual, Laser Fluorescence, Near-infrared Light Transillumination, and Digital Radiography in the Diagnosis of Occlusal Enamel Caries in Primary Teeth: An <i>In Vitro</i> Study. [PDF]
Int J Clin Pediatr DentGerard LM, Sridhar N.
europepmc +1 more source
A 3D‐Printed Model of Human Lactation
Advanced Healthcare Materials, EarlyView.Breastfeeding supports infant and maternal health, yet in vitro models that mimic human lactation remain scarce. Here, light‐based 3D printing creates high‐resolution, alveoli‐inspired microwells that guide breast cells into polarized microtissues. The printed scaffolds embed slow‐release prolactin microcrystals to deliver hormonal cues, enabling human
Amelia Hasenauer, Marcy Zenobi‐Wong
wiley +1 more source
Hemodynamic Assessment Using SPY Laser Fluorescence Imaging During Pancreatoduodenectomy with Common Hepatic Artery Resection. [PDF]
Ann Surg OncolFuji T +7 more
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.Using a tooth‐on‐a‐chip model that recreates interactions between dental epithelial and mesenchymal cells, the authors show that sequential FGF10+BMP4, BMP2, and Emdogain produce distinct, biologically consistent regenerative responses. The platform recapitulates known signal‐specific effects and, for the first time, reveals an influence of Emdogain on
Chong Huang +3 more
wiley +1 more source
Assessment of the correlation between fluorescence-featured intraoral scanner, laser fluorescence and spectrophotometric analyses in caries-affected dentin: an in-vitro diagnostic accuracy study. [PDF]
Lasers Med SciKanar Ö, Korkut B, Tağtekin D.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.ART@PLGA@GH‐A microspheres are developed via microfluidic technology for intra‐articular delivery of artemisinin. The system remodels rheumatoid arthritis microenvironments by regulating metabolic and inflammatory disorders, reducing lactate‐driven histone lactylation and cellular senescence, while restoring cartilage homeostasis and protecting joint ...
Shijie Meng +10 more
wiley +1 more source
Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization
Advanced Materials, EarlyView.A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab +8 more
wiley +1 more source
Blue Laser Source for Laser-Induced Fluorescence [PDF]
, 2008 Laser-induced fluorescence is a clinical diagnostic tool, used for tumor demarcation and detection. The technique relies on the injection or topical application of a light sensitive drug called a photosensitizer. This substance has the ability to be accumulated to higher concentrations in cancer cells than in normal cells.
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Laser fluorescence assessment of dental caries arrest with two silver fluoride agents in patients with special needs- a preliminary report. [PDF]
Lasers Med SciSee L +5 more
europepmc +1 more source