Results 41 to 50 of about 2,483,144 (287)
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Applied SciencesBackground: Early detection and monitoring of enamel changes during caries lesion formation are essential for preventive management. This study aimed to evaluate time-dependent enamel demineralization using micro-computed tomography (micro-CT) and to ...
Mirela Marinova-Takorova +9 more
doaj +1 more source
Fluorescence efficiency of laser dyes
Journal of Research of the National Bureau of Standards Section A: Physics and Chemistry, 1976 The fluorescence efficiency of xanthene dyes, oxazine dyes, and 7-aminocoumarins is discussed. Relations with the molecular structure are pointed out and dependence on solvent and temperature is explained. Several new fluorescence standards are suggested.
openaire +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Application of laser-based instrumentation for measurement of time-resolved temperature and velocity fields in the thermoacoustic system [PDF]
, 2010 This work aims to develop reliable laser-based measurement techniques to enable fundamental heat transfer and fluid flow studies in thermoacoustic systems.
Yu, Z. +8 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Laser Induced Fluorescence [PDF]
Laser Chemistry, 1990 Laser induced fluorescence (LIF) has become a common detector of atoms and molecules allowing to determine their internal state distributions. In this paper we mention the advantages of both kinds of lasers, cw or pulsed. We review some aspects of the LIF process, such as saturation or polarization effects, which could alter the results if they were ...
openaire +1 more source
Optical micromanipulation using ultrashort pulsed laser sources [PDF]
, 2007 In this thesis two previously separate fields of study are brought together: optical micromanipulation and ultrashort laser research. Here, the benefits of combining the high peak powers of ultrashort pulsed lasers and conventional optical ...
Little, Helen
core +2 more sources
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
XUV Fluorescence Detection of Laser-Cooled Stored Relativistic Ions
Atoms, 2023 An improved moveable in vacuo XUV fluorescence detection system was employed for the laser cooling of bunched relativistic (β = 0.47) carbon ions at the Experimental Storage Ring (ESR) of GSI Helmholtzzentrum Darmstadt, Germany.
Ken Ueberholz +24 more
doaj +1 more source