Results 131 to 140 of about 30,011 (264)

Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma

open access: yesAdvanced Healthcare Materials, EarlyView.
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett   +7 more
wiley   +1 more source

High power ultrafast phase-locked laser at 2060 nm from a doubly resonant optical parametric oscillator. [PDF]

open access: yesSci Rep
Rao H   +6 more
europepmc   +1 more source

Mechanically Compliant, Precision‐Porous Brain Implants Reduce the Foreign Body Reaction and Guide Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
This study explores how the brain responds to implants of different properties. Hydrogels with various mechanical properties and pore sizes were implanted in adult rat brains. It is observed that hydrogels with mechanical property closely matched to the brain and 40 µm pore size elicit a pro‐healing response from the brain by modulating the immune ...
Ian Dryg   +8 more
wiley   +1 more source

Octave spanning operation of visible to SWIR integrated coil-stabilized Brillouin lasers. [PDF]

open access: yesLight Sci Appl
Song M   +9 more
europepmc   +1 more source

Wearable OLED‐Assisted Photodynamic Cancer Therapy Using Chlorin e6‐Loaded Pluronic Nanocapsules as Photosensitizers

open access: yesAdvanced Healthcare Materials, EarlyView.
A novel photodynamic therapeutic approach has been employed for anticancer therapy, utilizing chlorin e6‐loaded Pluronic nanocapsules and a wearable organic light‐emitting diode light source. This has shown significant in vivo antitumor efficacy with minimal off‐target toxicity. The innovative combination of a wearable light source and photosensitizers
Hyeryeon Oh   +7 more
wiley   +1 more source

Multifunctional Thiolated Hyaluronic Acid‐graft‐PEDOT Dressing With Antifouling, On‐Demand Drug Delivery and Electrical Stimulation for Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
A multifunctional P(EDOT‐co‐EDOT‐g‐THA) dressing acts as a dynamic biointerface integrating antifouling capability, on‐demand drug delivery, and electrical stimulation. It achieves electrochemically triggered thiolated hyaluronic acid (THA) release while modulating cellular responses for wound healing application.
Jingwen Yang   +8 more
wiley   +1 more source

Inhibition of VEGF‐Induced Angiogenesis and Vascular Leakage by Bicistronic Co‐Expression of Aflibercept and COMP‐Ang1

open access: yesAdvanced Healthcare Materials, EarlyView.
A bicistronic rAAV8 vector encoding Aflibercept (Afb) and COMP‐cAng1 simultaneously coordinates VEGF clearance and Tie2‐mediated vessel maturation. In a 3D angiogenesis‐on‐a‐chip model, rAAV8‐Afb/cAng1 effectively reverses pathological barrier breakdown under clinical disease‐mimicking challenges.
Bong‐Kyu Kim   +9 more
wiley   +1 more source

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