Results 211 to 220 of about 14,580 (274)

Gβγ subunit activation of KV7 and BKCa channels underlies calcitonin gene‐related peptide vasorelaxation in myogenic rat coronary resistance arteries

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose CGRP is a potent, clinically relevant coronary vasodilator known to play a role in cardioprotection. Here, we investigated the precise intracellular signalling pathways leading to vasodilation in small coronary arteries.
Lucy A. Donovan   +4 more
wiley   +1 more source

Shared and specific molecular mechanisms of proteasome inhibitors in chemotherapy‐induced peripheral neurotoxicity

open access: yesBritish Journal of Pharmacology, EarlyView.
This study compares the molecular mechanisms of chemotherapy‐related peripheral neurotoxicity of two proteasome inhibitors, bortezomib and carfilzomib, using a multidisciplinary approach to reveal that, alongside shared effects on mitochondria structure and function, the more neurotoxic drug BTZ has specific effects on microtubules and mitochondrial ...
Federico Iseppon   +27 more
wiley   +1 more source

European Society of Contact Dermatitis Guideline for Diagnostic Patch Testing—Recommendations on Best Practice (Update 2026)

open access: yesContact Dermatitis, EarlyView.
ABSTRACT The present guideline updates the initial ESCD patch testing guideline, summarizing all aspects of patch testing for the diagnosis of contact allergy in patients suspected of suffering, or having been suffering, from allergic contact dermatitis or other delayed‐type hypersensitivity skin and mucosal conditions. Sections with brief descriptions
Wolfgang Uter   +23 more
wiley   +1 more source

Delipidisation of wool fibres and the subsequent beneficial properties of delipidised wool fibres

open access: yesColoration Technology, EarlyView.
Abstract Wool fibres are complex matrices of proteins and fatty acids/lipids found both internally and externally. 18‐methyleicosanoic acid (18‐MEA) is covalently bound to the surface of the fibre via a thio‐ester link, and is considered one of the most important lipids as it is responsible for the hydrophobic properties of wool fibres.
Jamie A. Hawkes, David M. Lewis
wiley   +1 more source

Limited elephant impacts on baobabs despite increasing elephant densities in a newly established protected area

open access: yesConservation Science and Practice, EarlyView.
Researchers combined aerial and ground surveys to map baobab distribution and assess elephant herbivory impacts on baobabs across Karingani Game Reserve, Mozambique. Researchers found that aerial surveys were an effective tool for mapping baobabs and that baobabs were more likely to occur closer to permanent water, at lower elevations, and in areas ...
Audrey Y. Chin   +4 more
wiley   +1 more source

Rare Secondary Neoplasms Arising in Epidermal Nevus: A Case Series and Literature Review

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Malignant transformation is known to occur with many nevi, such as nevus sebaceus. However, cases of secondary tumors developing in an epidermal nevus (EN) are rare, with only a few case reports documented in the literature. We present three unique cases of syringocystadenoma papilliferum (SCAP), syringofibroadenoma, trichilemmoma, and basal ...
Haya A. Homsi   +5 more
wiley   +1 more source

Retrospective case series of two‐stage folded paramedian forehead flap nasal reconstruction without cartilage grafts

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Full‐thickness nasal defects of the tip, soft triangle, and ala are commonly reconstructed using a paramedian forehead flap with cartilage grafts or an epithesis. However, these approaches may be associated with donor‐site morbidity and psychological burden.
Conrad Hempel   +3 more
wiley   +1 more source

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