Results 101 to 110 of about 841,302 (305)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Strongly aligned gas-phase molecules at Free-Electron Lasers

, 2015
We demonstrate a novel experimental implementation to strongly align molecules at full repetition rates of free-electron lasers. We utilized the available in-house laser system at the coherent x-ray imaging beamline at the Linac Coherent Light Source ...
Aquila, Andy, Barty, Anton, Bean, Richard, Boll, Rebecca, Boutet, Sébastien, Bucksbaum, Philip, Chapman, Henry N., Christensen, Lauge, Fry, Alan, Hunter, Mark, Kierspel, Thomas, Koglin, Jason E., Küpper, Jochen, Liang, Mengning, Mariani, Valerio, Morgan, Andrew, Mullins, Terry, Natan, Adi, Petrovic, Vladimir, Robinson, Joseph, Rolles, Daniel, Rudenko, Artem, Schnorr, Kirsten, Stapelfeldt, Henrik, Stern, Stephan, Thøgersen, Jan, Trippel, Sebastian, Wang, Fenglin, Wiese, Joss, Yoon, Chun Hong   +29 more
core   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Identification of semen traces at a crime scene through Raman spectroscopy and machine learning

Scientific Reports
Biological fluid stains can be instrumental in solving crimes. Identification of semen can help reconstruct events in sexual assault cases and identify suspects via DNA profiling.
Alexey V. Borisov, Mikhail S. Snegerev, Sonivette Colón-Rodríguez, Marisia A. Fikiet, Igor K. Lednev, Yury V. Kistenev   +5 more
doaj   +1 more source

Enhancing Corrosion Resistance and Mechanical Strength of 3D‐Printed Iron Polylactic Acid for Marine Applications via Laser Surface Texturing

Advanced Engineering Materials, EarlyView.
Laser surface texturing significantly improves the corrosion resistance and mechanical strength of 3D‐printed iron polylactic acid (Ir‐PLA) for marine applications. Optimal laser parameters reduce corrosion by 80% and enhance tensile strength by 25% and ductility by 15%.
Mohammad Rezayat, Mojtaba Karamimoghadam, Mohammadreza Lalegani Dezaki, Ali Zolfagharian, Giuseppe Casalino, Antonio Mateo, Mahdi Bodaghi   +6 more
wiley   +1 more source

Fibre orientations in collagen-containing tissues revealed with computational scattered light imaging and polarimetric second harmonic generation microscopy

Scientific Reports
Collagen forms dense fibre networks in the human body, with the organisation directly influencing tissue mechanics and function in health and disease.
Loes Ettema, Viktoras Mažeika, Mehdi Alizadeh, Hamed Abbasi, Virginijus Barzda, Miriam Menzel   +5 more
doaj   +1 more source

Blue laser imaging endoscopy system for the early detection and characterization of colorectal lesions: a guide for the endoscopist

Therapeutic Advances in Gastroenterology, 2016
Blue laser imaging is a new system for image-enhanced endoscopy using laser light. Blue laser imaging utilizes two monochromatic lasers (410 and 450 nm) instead of xenon light.
Kazutomo Togashi, Daiki Nemoto, Kenichi Utano, Noriyuki Isohata, Kensuke Kumamoto, Shungo Endo, Alan K. Lefor   +6 more
doaj   +1 more source

The Progress in Photoacoustic and Laser Ultrasonic Tomographic Imaging for Biomedicine and Industry: A Review

Applied Sciences, 2018
The current paper reviews a set of principles and applications of photoacoustic and laser ultrasonic imaging, developed in the Laser Optoacoustic Laboratories of ILIT RAS, NUST MISiS, and ILC MSU.
Anton Bychkov, Varvara Simonova, Vasily Zarubin, Elena Cherepetskaya, Alexander Karabutov   +4 more
doaj   +1 more source