Results 61 to 70 of about 841,302 (305)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

A Low-Cost Modulated Laser-Based Imaging System Using Square Ring Laser Illumination for Depressing Underwater Backscatter

Photonics
Underwater vision data facilitate a variety of underwater operations, including underwater ecosystem monitoring, topographical mapping, mariculture, and marine resource exploration.
Yansheng Hao, Yaoyao Yuan, Hongman Zhang, Shao Zhang, Ze Zhang   +4 more
doaj   +1 more source

THz-Enhanced DC Ultrafast Electron Diffractometer

Ultrafast Science, 2021
Terahertz- (THz-) based electron manipulation has recently been shown to hold tremendous promise as a technology for manipulating and driving the next generation of compact ultrafast electron sources.
Dongfang Zhang, Tobias Kroh, Felix Ritzkowsky, Timm Rohwer, Moein Fakhari, Huseyin Cankaya, Anne-Laure Calendron, Nicholas H. Matlis, Franz X. Kärtner   +8 more
doaj   +1 more source

Characterizing gas flow from aerosol particle injectors

, 2017
A novel methodology for measuring gas flow from small orifices or nozzles into vacuum is presented. It utilizes a high-intensity femtosecond laser pulse to create a plasma within the gas plume produced by the nozzle, which is imaged by a microscope ...
Horke, Daniel, Küpper, Jochen, Roth, Nils, Worbs, Lena   +3 more
core   +2 more sources

Measuring the temporal coherence of an atom laser beam [PDF]

, 2001
We report on the measurement of the temporal coherence of an atom laser beam extracted from a $^{87}$Rb Bose-Einstein condensate. Reflecting the beam from a potential barrier creates a standing matter wave structure.
A. L. Schawlow, A. P. Chikkatur, B. P. Anderson, C. C. Bradley, C. C. Bradley, C. Raman, C. S. Adams, D. S. Hall, E. W. Hagley, E. W. Hagley, H. M. Wiseman, I. Bloch, I. Bloch, I. Bloch, I. Bloch, J. Stenger, K. B. Davis, L. D. Landau, M. H. Anderson, M. R. Andrews, M.-O. Mewes, Michael Köhl, R. Graham, T. Esslinger, T. Esslinger, Theodor W. Hänsch, Tilman Esslinger, V. V. Nesvizhevsky, Y. Yapha   +28 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Study of high power CBC fiber laser systems with non-equal splitting ratio beam-splitters

Results in Optics, 2023
High power coherent beam combination (CBC) with non-equal splitting ratio beam splitters (BS) is studied. A BS-based two-channel CBC laser system has been built, and experiments with 50:50 BS and 30:70 BS has been carried.
Yuefang Yan, Rumao Tao, Haokun Li, Chun Zhang, Qiuhui Chu, Min Li, Jianjun Wang, Wenhui Huang, Feng Jing   +8 more
doaj   +1 more source

Non-destructive spatial heterodyne imaging of cold atoms [PDF]

, 2000
We demonstrate a new method for non-destructive imaging of laser-cooled atoms. This spatial heterodyne technique forms a phase image by interfering a strong carrier laser beam with a weak probe beam that passes through the cold atom cloud.
Anderson, Anderson, Andrews, Andrews, Bradley, Bradley, Davis, J. Sebby, Ketterle, R. Newell, S. Kadlecek, Savalli, T. G. Walker   +12 more
core   +2 more sources

Vessel packaging effect in laser speckle contrast imaging and laser Doppler imaging [PDF]

Journal of Biomedical Optics, 2017
Laser speckle-based techniques are frequently used to assess microcirculatory blood flow. Perfusion estimates are calculated either by analyzing the speckle fluctuations over time as in laser Doppler flowmetry (LDF), or by analyzing the speckle contrast as in laser speckle contrast imaging (LSCI).
Ingemar, Fredriksson, Marcus, Larsson
openaire   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source