Results 131 to 140 of about 2,739,050 (267)

Driving Drugs Deeper: Force‐Driven Microneedle Systems for Active Therapy and Their Road Towards Clinical Implementation

Small, EarlyView.
Force‐driven microneedles are presented as active therapeutic microdevices that overcome the diffusion limits of conventional patches. By integrating gas generation, magnetic actuation, cavitation, or iontophoresis, these systems drive payloads deeper into tissue, enabling faster, more controlled delivery and highlighting key design principles and ...
Majed Amini, Phoebe Li, Hamed Shahsavan, Mahla Poudineh   +3 more
wiley   +1 more source

Revealing Airflow–Particle Dynamics in Dry Powder Inhalers

Small, EarlyView.
An integrated framework combining device and formulation characterization, CFD–DEM simulations, and interpretable machine learning is established. This framework reveals how airflow and particle interactions govern powder dispersion across prevailing dry powder inhalers.
Jiale Chen, Ziyi Fan, Qingliang Yang, Yuanyuan Shao, Dongbing Li, Xiaoyang Wei, Xiang Luo, Kaiqi Shi, Gang Yang, Gensheng Yang, Ying Ma, Yuqing Ye, Jesse Zhu   +12 more
wiley   +1 more source

Laser powder bed fusion recoater selection guide: comparison of resulting powder bed properties and part quality [PDF]

Spreading devices used to create powder layers in the laser powder bed fusion of metals (PBF-LB/M) were found to have a significant impact on the additive manufacturing process.
Seidel, Christian, Horn, Max, Schlick, Georg, Schlick, Georg Josef, Schmitt, Matthias, Langer, Lukas   +5 more
core   +1 more source

Influence of Heat Treatment and Scan Rotation on the Microstructure of Hot Work Tool Steel Manufactured using Laser Powder Bed Fusion

steel research international, EarlyView.
The study investigates the influence of heat treatment and scan rotation on the microstructure of a modified H13 tool steel manufactured using laser powder bed fusion. Key findings include the refinement of prior austenite grains (PAGs) due to recrystallization and carbide pinning, and the significant impact of scan rotation on the size distribution of
Negar Panahi, Fengxiang Lin, Christos Oikonomou, Mikael Grehk   +3 more
wiley   +1 more source

Additive Manufacturing of Hot‐Work Tool Steel by In Situ Alloying Using Laser Powder Bed Fusion and Directed Energy Deposition—Strategies to Improve Chemical Homogeneity

steel research international, EarlyView.
To support future alloy development a powder mixture is processed by laser additive manufacturing. The powder mixture containing Mo‐ and W‐rich tracers is processed by powder bed fusion using single and double laser exposure and by directed energy deposition which provides drastically enlarged melt pools.
Felix Großwendt, Sebastian Weber, Jonathan Lentz   +2 more
wiley   +1 more source

HWTS 50 Tool Steel Tailored for Laser Powder Bed Fusion: Sliding Wear of Bare Surfaces and Nitriding Response in Comparison with 18Ni300 and AISI H13

steel research international, EarlyView.
This work investigates the wear resistance and nitriding behavior of PBF‐LB/M‐processed Osprey HWTS 50, a lean hot work tool steel. Three heat treatment conditions are compared to conventional wrought H13, H11, and PBF‐LB/M 18Ni300. The study highlights HWTS 50's enhanced nitrogen diffusion, deeper nitriding hardness depth, and comparable or improved ...
Jonathan Hann, Giorgia Lupi, Sylvain Dossin, Riccardo Casati, Mandanà Moshiri, Arne Röttger, Faraz Deirmina   +6 more
wiley   +1 more source

Fatigue Strength in Additive Toolmaking: A Study of Metal Binder Jetting and Electron Beam Melting for Processing Carbide‐Rich Cold‐Work Tool Steels

steel research international, EarlyView.
Focusing on the critical tap hole region of the blast furnace, this work examines binder characteristics, prepares tap hole clay with different formulations, and evaluates their physical properties. The findings confirm the advantages of composite binders and offer a new binder option for tap hole clay.
Frederik Tegeder, Lennart Mirko Scholl, Sandra Wieland, Christian Weck, Marie Franke‐Jurisch, Alexander Bezold, Thomas Weißgärber, Christoph Broeckmann   +7 more
wiley   +1 more source

In Situ Alloying of H13 Tool Steel With TiC via PBF‐LB/M

steel research international, EarlyView.
H13 tool steel is in situ alloyed with titanium carbides (TiC) in amounts up to 30 wt.%. This approach offers the advantage that the carbides melt only partially during processing, preventing excessive carbon enrichment of the steel matrix. The resulting microstructure consists of coarse, undissolved and fine, reprecipitated carbides, leading to grain ...
Oliver Bürgi, Anke Kaletsch, Christoph Broeckmann   +2 more
wiley   +1 more source

Tailoring Laser Powder Bed Fusion and Post‐Processing Parameters for JIS SKD61 Tool Steels: Surface Roughness, Microstructure, and Mechanical Properties

steel research international, EarlyView.
Laser powder bed fusion of JIS SKD61 tool steel is systematically optimized using a Taguchi design and ANOVA. Hatch spacing and layer thickness are identified as dominant parameters controlling surface roughness and tensile strength. Subsequent tempering at 600°C improves microstructural stability and mechanical performance, enabling high‐density SKD61
Masrurotin Masrurotin, Andi Ard Maidhah, Maziar Ramezani, Wojciech Macek, Cho‐Pei Jiang   +4 more
wiley   +1 more source

Tailored Hardening and Isothermal Bainitizing of Additively Manufactured Nitrogen‐Enhanced Martensitic Chromium Steel

steel research international, EarlyView.
Tailored heat treatments transform additively manufactured high‐nitrogen martensitic Cr steel from austenitic as‐built condition to high‐hardness states. Isothermal bainitizing at 250°C generates an ultrafine nanostructure and achieves higher hardness than conventional hardening and tempering, highlighting a promising postprocessing route for laser ...
Philip König, Sebastian Weber, Jonathan Lentz   +2 more
wiley   +1 more source