Results 61 to 70 of about 2,275,673 (297)
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Geometrical Accuracy Investigations of Handheld 3D Scanners in Comparison: Low-Cost vs. High-End [PDF]
Handheld 3D scanners have gained increasing importance in recent years due to their flexibility and declining acquisition costs. While high-end systems provide standardized accuracy specifications, affordable devices often lack reliable and comparable ...
T. P. Kersten +2 more
doaj +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
2-Photon Laser Scanning Microscopy on Native Human Cartilage [PDF]
Martini J, Tönsing K, Dickob M, Anselmetti D. 2-Photon Laser Scanning Microscopy on Native Human Cartilage. In: Proceedings of SPIE - The International Society for Optical Engineering. Vol 5860.
Michael Dickob +7 more
core +1 more source
Geometric Accuracy Investigations of Mobile Phone Devices in the Laboratory Using High-Precision Reference Bodies [PDF]
The sensors in modern mobile phones (running either the Android or iOS operating system) have become increasingly sophisticated, to the extent that they can be used as measuring systems for a wide range of applications.
T. P. Kersten +2 more
doaj +1 more source
A workflow for the photogrammetric combination of non-invasive multispectral imaging techniques ranging from ultraviolet (UV) and visible (VIS) to near infrared (NIR) for the investigation of wall paintings is presented.
Max Rahrig +2 more
doaj +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Scanning laser techniques for characterisation of different surface breaking defect geometries [PDF]
Measurements using a laser scanning system consisting of a pulsed Nd:YAG laser to generate surface ultrasonic waves and an interferometer to detect the surface displacement, are presented for different samples and defect geometries.
Edwards, R. S. (Rachel S.) +4 more
core
MEASURING LEAF WATER CONTENT USING MULTISPECTRAL TERRESTRIAL LASER SCANNING [PDF]
Climate change is increasing the amount and intensity of disturbance events, i.e. drought, pest insect outbreaks and fungal pathogens, in forests worldwide. Leaf water content (LWC) is an early indicator of tree stress that can be measured remotely using
S. Junttila +15 more
doaj +1 more source
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source

