Results 191 to 200 of about 4,852,844 (283)

Astrocytes Coordinate Neurovascular Coupling During Prolonged Sensory Demand via AQP4/TRPA1/BEST1/D‐Serine Signaling

Advanced Science, EarlyView.
Neuronal activation leads to astrocytic transient volume changes, activating transient receptor potential ankyrin 1 (TRPA1) channels, leading to Ca2+ influx. Activation of TRPA1 causes the release of D‐serine through BEST1. Finally, the augmented extracellular levels of D‐serine boost neuronal activity by binding GluN1‐containing NMDARs, leading to CBV
Kayoung Han, Minwoo Wendy Jang, Taeyoung Park, Ki Jung Kim, Victor James Drew, Sunpil Kim, Tai Young Kim, Mingu Gordon Park, Myeongju Kim, Seung Won Chung, Minah Suh, C. Justin Lee   +11 more
wiley   +1 more source

Mapping of blood flow and slow speckle tissue dynamics using laser speckle contrast imaging. [PDF]

Biomed Opt Express
Liu B, Tang RP, Long EA, Yaqoob Z, Simkulet MG, Postnov DD, Erdener ŞE, Boas DA, Cheng X.   +8 more
europepmc   +1 more source

Programmable Self‐Heating Microneedle Patch for on‐Demand Postprandial Glucose Management

Advanced Science, EarlyView.
A programmable self‐heating microneedle patch enables on‐demand, timed‐sequence insulin delivery via user‐triggered quadrant activation. Each activation generates localized heat that melts a phase‐change barrier, accelerating drug release. In diabetic rats, sequential quadrant activation counteracts four meal‐mimicking glucose spikes over 24 h without ...
Yang Zhao, Guifang Pan, Jincai Zhang, Yue Gong, Wenjian Zhang, Huiling Shen, Xingxing Li, Yuehan Ouyang, Hanhan Xie, Jundong Shao   +9 more
wiley   +1 more source

Enhancement of vascular visualization in laser speckle contrast imaging based on image algorithms. [PDF]

J Biomed Opt
Yan L, Du G, Huang X, Xiao Y, Bian J, Zhang Y, Hou H, Min M, Chen X.   +8 more
europepmc   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

Advancing intraoperative cerebral blood flow monitoring: integrating imaging photoplethysmography and laser speckle contrast imaging in neurosurgery. [PDF]

Front Optoelectron
Kamshilin AA, Konovalov AN, Grebenev FV, Kozlov IO, Stavtsev DD, Piavchenko GA, Nippolainen E, Zaytsev VV, Sokolov AY, Telyshev DV, Kuznetsov SL, Romashko RV, Meglinski IV.   +12 more
europepmc   +1 more source

Conjugated Polymer‐Microbe Interactions Trigger Regulatory Reprogramming for Enhanced Bioelectrocatalysis

Advanced Science, EarlyView.
Conjugated polymer‐supported bioelectrochemical systems are shown to enhance microbial electrosynthesis by triggering coordinated electrochemical, transcriptional, post‐transcriptional (sRNA), metabolic, and protein‐level responses. Integrated multi‐omics and electrochemical analyses reveal selective physiological remodeling associated with improved ...
David Ohayon, Yuanmei Liang, Zexuan Wang, Jee Loon Foo, Glenn Quek, Samantha R. McCuskey, Zhongxin Chen, Matthew Wook Chang, Guillermo C. Bazan   +8 more
wiley   +1 more source

Time-Resolved Laser Speckle Contrast Imaging (TR-LSCI) of Cerebral Blood Flow. [PDF]

IEEE Trans Med Imaging
Fathi F, Mazdeyasna S, Singh D, Huang C, Mohtasebi M, Liu X, Rabienia Haratbar S, Zhao M, Chen L, Can Ulku A, Mos P, Bruschini C, Charbon E, Chen L, Yu G.   +14 more
europepmc   +1 more source

Glutaminolysis Blockade‐Empowered Bimodal Nanodepot for Spatially Complementary Sono‐Thermal Ablation via PANoptosis and STING Activation Against Large Tumors

Advanced Science, EarlyView.
An injectable bimodal TCPD nanodepot disrupts glutaminolysis and TCA metabolism, sensitizing large tumors to spatially complementary sono‐thermal ablation for complete treatment coverage. This intervention induces mitochondrial and endoplasmic reticulum dysfunction, genotoxicity, and NAD+ depletion, converging to trigger PANoptosome assembly and ...
Yi‐Ming Liu, Juan Qin, Si‐Yuan Wu, Xue‐Zhen Zhu, Yun‐Fei Cai, Pei‐Yao Sun, Hao Yang, Xing‐Yue Wang, Shu Li, Duo Wang, Hai‐Dong Zhu   +10 more
wiley   +1 more source

Effect of Orthodontic Force on Gingival Blood Flow Measured by Laser Speckle Contrast Imaging: A Randomised Controlled Trial. [PDF]

Int Dent J
Yin F, Zhao J, Zhang H, Wang S, An Q, Wei X, Tang C, Han S.   +7 more
europepmc   +1 more source