CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation
ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu +10 more
wiley +1 more source
Cellular homeostasis and oncology safety of low pulse frequency laser for photobiomodulation in oral and dermal cells. [PDF]
Real-Lopez DA +4 more
europepmc +1 more source
Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation
An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng +10 more
wiley +1 more source
Low Level Laser Therapy: A Concise Review on its Applications
Aneetha Raman +5 more
doaj
Causal digital twin modeling of periodontal healing: personalized prediction of low-level laser therapy benefit using a tooth-graph ODE transformer. [PDF]
Natarajan PM, Yadalam PK.
europepmc +1 more source
PRC2.1(PCL2)‐coordinated H3K27me3‐enriched PNH establishes a spatial scaffold crucial for nucleolar integrity. As a crucial coordinator, PCL2 links PRC2.1 to chromatin organization and NPM1 assembly. This network‐based model reveals how chromatin modifications and nucleolar components cooperatively maintain nucleolar architecture, revealing novel ...
Lina Zhu +12 more
wiley +1 more source
Comparison of laser therapy and extracorporeal shock wave therapy in the treatment of patients with plantar fasciitis: a systematic review and meta-analysis of prospective studies. [PDF]
Alotaibi MN +8 more
europepmc +1 more source
Role of laser therapy in enhancing chemotherapy efficiency in breast cancer: low level laser therapy, photochemotherapy, and photodynamic therapy as promising treatments. [PDF]
Mohamed AE +3 more
europepmc +1 more source
Early Phase Gingival Wound Healing Following Low-Level Er:YAG Laser Irradiation: In Vitro and In Vivo Studies. [PDF]
Chen L +6 more
europepmc +1 more source

