Results 81 to 90 of about 264,511 (262)

Programming Nanoscale Reaction Environments via Peptide Localization for Gold Nanoparticle Growth in Liposomal Nanoreactors

Advanced Functional Materials, EarlyView.
The liposome nanoreactor method enables uniform metal nanoparticle synthesis using the interior as a reaction environment. We demonstrate that peptide sequences and lipid compositions act as a functional molecular switch to control reaction environments in liposome nanoreactors.
Yuya Abe, Joseph Fox, Zabeada Aslam, Kevin Critchley, Stephen D. Evans, Mina Okochi, Masayoshi Tanaka   +6 more
wiley   +1 more source

Low-level laser facilitates alternatively activated macrophage/microglia polarization and promotes functional recovery after crush spinal cord injury in rats

Scientific Reports, 2017
Macrophages and resident microglia play an import role in the secondary neuroinflammation response following spinal cord injury. Reprogramming of macrophage/microglia polarization is an import strategy for spinal cord injury restoration.
Ji Wei Song, Kun Li, Zhuo Wen Liang, Chen Dai, Xue Feng Shen, Yu Ze Gong, Shuang Wang, Xue Yu Hu, Zhe Wang   +8 more
doaj   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Nitride MXenes Beyond Carbides: Bridging the Gap Between Computational Prediction and Experimental Realization

Advanced Functional Materials, EarlyView.
Nitride MXenes remain constrained by a persistent gap between computational prediction and experimental realization. This Review identifies the thermodynamic, kinetic, and chemical barriers limiting their synthesis, critically evaluates emerging fabrication routes, and proposes a multidimensional computational‐experimental framework to accelerate the ...
Naresh Varnakavi, Masoud Soroush
wiley   +1 more source

Effects of optogenetic stimulation on neural gene expression in human bone marrow and adipose-derived mesenchymal stem cells

BMC Biotechnology
Background Bone Marrow-derived Mesenchymal Stem Cells (BM-MSCs) and adipose tissue are widely applied in tissue engineering. Optogenetics enables millisecond-scale spatial and temporal control of particular cell populations.
Mohammad Amin Fereidounian, Shahriyar Bourbour, Afshan Shirkavand, Hoda Keshmiri Neghab, Mahdi Saberi Pirouz, Ezeddin Mohajerani, Shirin Farivar   +6 more
doaj   +1 more source

Efficacy of Laser Therapy in Patient Self-Assessment for Cervical and Lumbar Spine Pain Syndromes – Original Study

Journal of Education, Health and Sport
Introduction: Laser therapy, or Light Amplification by Stimulated Emission of Radiation (LASER), is a relatively popular method used in rehabilitation for various patient conditions.
Damian Ruta
doaj   +1 more source

XTRUDE: A Process‐Informed Framework for High‐Fidelity Analysis of Hydrogel Extrusion

Advanced Functional Materials, EarlyView.
Extrusion performance emerges from the interplay between material properties and processing conditions. XTRUDE (eXTrusion Rheology for Understanding and Defining Extrudability) recreates the extrusion environment with in situ pressure and temperature sensing, enabling characteristic pressure signatures to quantify extrusion‐specific phenomena and ...
Farhad Sanaei, Pascal Bertsch, Juliette Lafosse, Sander C. G. Leeuwenburgh, Mani Diba   +4 more
wiley   +1 more source

Guanosine‐Quadruplex Hydrogels as Dynamic, Mechanically Tunable and Ion Conductive 3D Scaffolds for Cell Culture Applications

Advanced Functional Materials, EarlyView.
Versatile guanosine‐quadruplex (GQ) hydrogels are developed as dynamic biomatrices for cell culture. These scaffolds are fabricated under mild aqueous conditions, present improved stability, tunable mechanical properties within physiological ranges; fibrillar, porous microstructure, ion conductivity, and cytocompatibility.
Neha Thakur, Minye Jin, Pavel Milkin, Deepa Negi, Carla Cofiño Fabres, Hubert Gojzewski, Leonid Ionov, Alla Synytska, Andries van der Meer, Robert Passier, Julieta I. Paez   +10 more
wiley   +1 more source

Critical Coupling in Semi‐Trasparent Fano Resonators for Photothermal Converters

Advanced Functional Materials, EarlyView.
An ultrathin metal–insulator multilayer architecture is engineered to exploit Fano‐resonant critical coupling, completely suppressing optical reflectance while achieving a balanced 50:50 trade‐off between absorbance and transmittance. Upon laser excitation at resonance, the metamaterial generates intense localized heat (ΔT≈550∘C$\Delta T {\approx }550^\
Giuseppe Emanuele Lio, Giuseppe Nicoletta, Roberto Caputo, Antonio Ferraro   +3 more
wiley   +1 more source