Results 41 to 50 of about 167,647 (295)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Quantitative analysis of the thermal distortions in a 100 W CW Nd:YAG ceramic slab laser [PDF]
Journal of the European Optical Society-Rapid Publications, 2007 Making use of an interferometric diagnostic system, we analyze the thermo-mechanical distortions taking place in the slab shaped ceramic Nd:YAG active medium of a 100 W class laser.
Lapucci A. +6 more
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Generation of Orthogonally Polarized Mode-Locked Lasers at Wavelength of 1342 nm
IEEE Photonics Journal, 2017 A mode-locked laser with orthogonal polarization at the wavelength of 1342 nm is experimentally achieved by using the natural birefringence of the Nd:YVO4 crystal.
Hsing-Chih Liang +4 more
doaj +1 more source
Recent Progress and Development Trend of Self-Sweeping Fiber Laser
Frontiers in Physics, 2021 Since 2011, when Kir’yanov et al. first reported a new wavelength self-sweeping ytterbium-doped fiber laser that does not rely on any tuning element but only on the dynamic induced grating generated in the gain fiber by the standing wave resonator ...
Zhenzhong Zuo +12 more
doaj +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
1.5 μm Solid-state Lasers with Diode Pumping [PDF]
Журнал нано- та електронної фізики, 2017 More robust 1.5 μm compact lasers are found. The results of experimental studies of the conditions of generation of the pulse laser with KGW:Nd3 +crystal with transverse pumping are presented.
Y.P. Machekhin, I.V. Beznosenko
doaj +1 more source
A Review of the High-Power All-Solid-State Single-Frequency Continuous-Wave Laser
Micromachines, 2021 High-power all-solid-state single-frequency continuous-wave (CW) lasers have been applied in basic research such as atomic physics, precision measurement, radar and laser guidance, as well as defense and military fields owing to their intrinsic ...
Weina Peng +5 more
doaj +1 more source
An insight into polarization states of solid-state organic lasers
, 2012 The polarization states of lasers are crucial issues both for practical applications and fundamental research. In general, they depend in a combined manner on the properties of the gain material and on the structure of the electromagnetic modes.
A. Brosseau +18 more
core +2 more sources
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source