Results 201 to 210 of about 160,127 (291)

Directional Liquid Transport Enabled pH‐Responsive Hierarchical Composite for Enhanced Wound Healing

Advanced Healthcare Materials, EarlyView.
A hierarchical composite with a gradient architecture transitioning from hydrophobic to hydrophilic layers integrates diode‐like liquid transport, efficient water absorption, breathability, and mechanical robustness. This device enables a multifunctional therapeutic platform with pH‐responsive dual‐drug release, providing synergistic anti‐inflammatory ...
Baolin Wang, Li‐Fang Zhu, Yuna Lang, Siyi Zhang, Fei Chen, Ming‐Wei Chang   +5 more
wiley   +1 more source

Genomic Characterization and Phylogenetic Relationships of Procypris rabaudi Revealed by Whole-Genome Survey Analysis. [PDF]

Animals (Basel)
Han X, Luo R, Liu Q, Yuan Z, He W.
europepmc   +1 more source

Common Signatures of Altered Gene Regulation and Invasiveness of Different Breast Cancer Cell Lines after Matrix Interface Crossing

Advanced Healthcare Materials, EarlyView.
Interface transmigration reprograms triple‐negative breast cancer cells, triggering a shared switch toward more aggressive and invasive phenotypes. Using a collagen I interface model, this study identifies shared transcriptional changes involving proliferation, chromatin remodeling, and DNA repair pathways.
Cornelia Clemens, Hannah Trampert, Nataliia Kotsiuba, Tilo Pompe   +3 more
wiley   +1 more source

Glacial Legacies-How Refugial Dynamics Shaped the Evolution of the Alpine Endemic Bush-Cricket Anonconotus italoaustriacus. [PDF]

Mol Ecol
Kirschner P, Kranebitter P.
europepmc   +1 more source

Ultrasound‐Triggered Nanobubbles for Endothelial‐Targeted Drug Delivery in the Detection and Treatment of Doxorubicin‐Induced Cardiotoxicity

Advanced Healthcare Materials, EarlyView.
The DA/VTP‐NBs selectively recognized cardiac ECs damaged by DIC and achieved cell‐level targeted imaging. Then US‐triggered controlled release successfully enabled the release of DAPA within the DA/VTP‐NBs at the site of injury. This precise on‐demand drug release approach amplifies a series of localized therapeutic effects through the mtDNA‐mediated ...
Jun Zhang, Yi Ling, Xin Li, Deng Liu, Li Dong, Xuemei Chen, Yingxin Sun, Yongning Shang, Yanli Guo   +8 more
wiley   +1 more source

Volcanism-induced collapse and recovery of the Atlantic meridional overturning circulation under glacial conditions. [PDF]

Sci Adv
Vettoretti G, Hu RJ, Bethke I, Krüger K, Sigl M, Outten S, Lin J, Nuterman R, Svensson A, Ditlevsen P, Jochum M.   +10 more
europepmc   +1 more source

Oxygen Supply of Islets of Langerhans by Photosynthetically Active Microalgae in Bioprinted Co‐Cultures Maintains Their Function in a Hypoxic Environment

Advanced Healthcare Materials, EarlyView.
This study developed a bioprinted co‐culture system embedding rat pancreatic islets and Scenedesmus sp. microalgae spatially defined in close vicinity. Red light was found optimal to ensure microalgal photosynthesis while maintaining islet viability and functionality. A tailored co‐culture medium supported both cell types.
Finn Dani, Sarah Duin, Ashwini Rahul Akkineni, Susann Lehmann, Barbara Ludwig, Michael Kühl, Michael Gelinsky, Anja Lode   +7 more
wiley   +1 more source

Quaternary climatic oscillations shaped the demographic history and triggered intraspecific divergence of Rhododendron shanii, a mid-montane endemic in eastern Asia. [PDF]

Front Plant Sci
Deng Y, Li Z, Hu Y, Li Z, Zhang S, Liu K, Shao J.   +6 more
europepmc   +1 more source

Bipolar volcanic ice-core synchronization of the entire last glacial period

Precise synchronization of paleoclimate records is essential for inferring the dynamics and past evolution of the climate system. For the last glacial period, the time scales of ice cores from the Greenland and Antarctic ice sheets have been synchronized by the use of cosmogenic radionuclides, atmospheric gas concentrations, and traces of large ...
Svensson, Anders, Vettoretti, Guido, Lin, Jia-mei, Sinnl, Giulia, Dahl-Jensen, Dorthe, Steffensen, Jorgen Peder, Rasmussen, Sune Olander, Vinther, Bo, Hvidberg, Christine S., Kjær, Helle Astrid, Gkinis, Vasileios, Cook, Eliza, Lohmann, Johannes Jakob, Melcher, Jonathan Ortved, Halkjær, Sune, Kipfstuhl, Sepp, Wilhelms, Frank, Adolphi, Florian, Fischer, Hubertus, Bigler, Matthias, Sigl, Michael, LANDAIS, Amaelle, Bouchet, Marie, Klüssendorf, Anna Maria, Parrenin, Frédéric, Mulvaney, Robert, Eric, Wolff, Burke, Andrea, Innes, Helen, Severi, Mirko, Buizert, Christo, McConnell, Joseph, Chellman, Nathan, Wensman, Sophia, Beer, Jürg, Oyabu, Ikumi, Muscheler, Raimund   +36 more
openaire   +1 more source

3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence

Advanced Healthcare Materials, EarlyView.
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes, Timo Rademakers, Ana Filipa Henriques Lourenço, Andrea Calore, Clarissa Tomasina, Denis van Beurden, Jinjie Venema, Bryan Chömpff, Hong Liu, Nicole Bouvy, Sandra Camarero‐Espinosa, Lorenzo Moroni   +11 more
wiley   +1 more source