Results 111 to 120 of about 5,862,672 (337)
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Microwave Sensors to Monitor the Displacement of Civil Structures: Recent Experimental Campaigns and Last Issues towards Advanced Sensors [PDF]
, 2017 Guido Luzi, Michele Crosetto
openalex +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
, 2010 The foundation of good end-of-life care involves assessment, education, treatment, and reassessment. Effective symptom management and attention to the quality of life for patients and families are the primary goals of palliative care. This care often shifts to the needs of the family such that communication and education about the dying process, the ...
Jane E. Loitman, Christian T. Sinclair
openaire +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Global experts 'off radar' [PDF]
, 2014 This issue of ABE Journal, which takes inspiration from a 2008 conference session as well as from the many conversations that took place within one of the working groups of the European funded COST-action “European Architecture beyond Europe,”1 seeks to ...
De Raedt, Kim, Lagae, Johan
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Photos from the Last Issue of the EMC Society Newsletter [PDF]
, 2021 Daniel D. Hoolihan
openalex +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Judgment Day for Fraud-on-the-Market: Reflections on \u3ci\u3eAmgen\u3c/i\u3e and the Second Coming of \u3ci\u3eHalliburton\u3c/i\u3e [PDF]
, 2013 The Supreme Court has reaffirmed the fraud on the market presumption of reliance, facilitating large scale class actions for this kind of securities fraud.
Langevoort, Donald C
core +2 more sources