Results 61 to 70 of about 1,465,091 (287)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The Last Issue - Volume 2, Issue 2

open access: yes, 1973
Archived web ...
The Last Issue Staff
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The Dispute over the Date of the Last Supper. Its Chronology Revisited

open access: yesVerbum Vitae, 2020
The article discusses the issue of alleged or real disagreements between John and the Synoptics regarding the dating of the Last Supper. After showing the elements of the Gospel narratives that portray the Last Supper as a paschal supper, the author ...
Mariusz Rosik
doaj   +1 more source

A response to “Last Drinks”

open access: yes, 2022
Recently when I was browsing the internet, I came across “Last Drinks” a YouTube video report presented by Tom Steinfort, a famous Australian journalist. The program was produced by 60 Minutes Australia.
Abdul Razak, Mohd Abbas
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The Last Issue - Volume 1, Issue 5

open access: yes, 1973
Archived web ...
The Last Issue Staff
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The Last Issue - Volume 2, Issue 3

open access: yes, 1973
Archived web ...
The Last Issue Staff
core  

Sea surface temperature changes in the southern California borderlands during the last glacial-interglacial cycle

open access: yes, 1996
A variety of evidence suggests that average sea surface temperatures (SSTs) during the last glacial maximum in the California Borderlands region were significantly colder than during the Holocene.
P. Graham Mortyn   +9 more
core   +1 more source

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