Results 101 to 110 of about 4,714,134 (281)
The Last Column in the 9-11 Museum
, 2020 To thousands of Ground Zero recovery workers, the Last Column represents a symbol of resilience after 9/11. Standing at 36-feet tall, the Last Column is a 58-ton beam that was part of the core structure of the South Tower.
Beards, Daniel E.
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Frances Tafoya and Stella (last name unknown)
, 1952 Frances Tafoya and Stella (last name unknown) walking on Central Ave. in Albuquerque. 'Albuquerque, New Mexico' printed at bottom of photo.
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FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Red Cross Officer Jack, Last Name Unknown
, 1942 Red Cross officer, Jack (last name illegible). Signed “Yours Sincerely” for Zofia Krzyżanowska (nee Zofia Wiśniewska; later: Zofia Drzewieniecki).
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Early physical trauma and subsequent disturbance in childhood [PDF]
, 1976 Forty-two case histories of emotionally disturbed preschool children were examined to determine if there was a relationship between physical trauma (severe illness, hospitalization, or accident) before the age of 3 years and subsequent childhood ...
Moskovitz, Jacquelyn
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Journal of Inflammation Research, 2019 Taheri M, Azimi G, Sayad A, et al. J Inflamm Res. 2018;11:457–463.On page 457, Author list and Correspondence, the last author’s name was misspelt.
Taheri M +6 more
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