Results 201 to 210 of about 4,714,134 (281)

SWM dataset: A large-scale annotated benchmark for <i>Sclerotinia sclerotiorum</i> object detection in white mold management. [PDF]

Data Brief
Pereira RC, Torres RDS, Neto JJD, Borges DL, Lobo M, Pedrini H.   +5 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Correction: A case series of confirmed Neisseria gonorrhoeae native mitral valve infective endocarditis: presentation and management. [PDF]

Eur Heart J Case Rep
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Erratum for "The Impact of Care Delivered Through the Self-Management Promotion Model on Health Literacy Levels in Patients with Chronic Obstructive Pulmonary Disease: Quasi-Experimental Research". [PDF]

Health Lit Res Pract
europepmc   +1 more source

Augmenting fact and date of death in electronic health records using internet media sources: a validation study from two large healthcare systems. [PDF]

Am J Epidemiol
LeNoue-Newton M, Al-Garadi M, Ngan K, Pillai H, Reeves RM, Park D, Westerman DM, Hernández-Muñoz JJ, Wang X, Kuzucan A, Wang SV, Lin KJ, Fuller CC, McPheeters M, Matheny ME, Desai RJ.   +15 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

From Cabinet to Catalogue: The Palaearctic bee (Hymenoptera, Apoidea, Anthophila) collection of the Museu Nacional de História Natural e da Ciência, Universidade de Lisboa, Portugal. [PDF]

Biodivers Data J
Baptista M, de Sousa P, Keller RA.
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Correction to "Moving beyond book values: Using machine learning to improve the accuracy of manure nutrient concentration predictions". [PDF]

J Environ Qual
europepmc   +1 more source