Results 151 to 160 of about 28,930 (262)

An Updated Case Report of a Long-Term Survivor With Stage IVB Ovarian Squamous Cell Carcinoma Arising From Mature Cystic Teratoma. [PDF]

J Obstet Gynaecol Res
Nagayama R, Okadome M, Shimamoto K, Koga Y, Taguchi K, Ariyoshi K.   +5 more
europepmc   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Marburg virus persistence and clinical complications among recovered persons in Rwanda: a longitudinal study protocol. [PDF]

BMJ Open
Ngabonziza J, Seruyange E, Mohamed NS, Brangel P, Tuyishime A, Choi MJ, Dahlke C, Remera E, Kagame J, Kreuger MJ, Ahmed A, Mwungura JC, Rwagasore E, Gishoma D, Bergeron É, Umulisa MM, Montgomery J, Mukagatare I, Rojek A, Musafiri S, Dowling W, Muvunyi CM.   +21 more
europepmc   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Three-Domain Serial Cranial Ultrasound Phenotypes and Outcomes in Very Preterm Infants with Severe Brain Injury: A Single-Center Cohort Study. [PDF]

Children (Basel)
Núñez-Enamorado N, Camacho-Salas A, López-Maestro M, Gallego-Herrero MC, Martínez de Aragón A, Vila-Bedmar S, Vázquez-Román S, Zamora-Crespo B, Pallás-Alonso CR, Moral-Pumarega MT.   +9 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Sexual health behaviors and contraceptive practices among Canadian childhood, adolescent, and young adult cancer survivors and controls. [PDF]

Cancer
de Beijer IAE, van den Oever SR, Lawal OA, Button A, Duong J, Adham H, Giles J, Reynolds K, Schulte FSM.   +8 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Prenatal Predictors of Fetal and Neonatal Death in Truncus Arteriosus: A Fetal Heart Society Research Collaborative Study. [PDF]

J Am Heart Assoc
Cox K, Husain N, Ansah D, Knight T, Channing A, Cuneo B, Dhanantwari P, Donofrio M, Geiger M, Howley L, Hornberger LK, Javeri S, Jones EG, Kaplinski M, Kavanaugh-McHugh A, Kiaffas M, Kosiv K, Laternser C, Low O, Moon-Grady AJ, Peyvandi S, Pinto N, Porlier A, Prosnitz A, Rao R, Schidlow D, Sinkovskaya E, Srinivasan R, Stiver C, Quezada E, Arya B, Patel S.   +31 more
europepmc   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source