Results 171 to 180 of about 46,872 (345)

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

Perception of Cognitive Functions and Academic Performance in Chilean Public Schools. [PDF]

open access: yesBehav Sci (Basel), 2022
Valdebenito-Villalobos J   +9 more
europepmc   +1 more source

Una estimación del coste marginal en bienestar del sistema impositivo en España [PDF]

open access: yes
Los sistemas impositivos no se adecuan en la práctica a las recomendaciones normativas de la teoría de la imposición óptima. Las dificultades son de dos tipos: una primera es de nivel informacional en cuanto al desconocimiento de los valores de los ...
Ferran Sancho
core  

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

[The value of human resources: experience of critical care nurses during the COVID-19 epidemic]. [PDF]

open access: yesEnferm Intensiva, 2022
González-Gil MT   +10 more
europepmc   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha   +4 more
wiley   +1 more source

ECG Data Analysis with Denoising Approach and Customized CNNs. [PDF]

open access: yesSensors (Basel), 2022
Mishra A   +7 more
europepmc   +1 more source

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