Results 71 to 80 of about 46,872 (345)
Jurassic Palynology from “The Dinosaur Coast” of Asturias (Lastres Fm., Northwestern Spain): Palynostratigraphical and Palaeoecological Insights [PDF]
, 2022 Artai A. Santos +4 more
openalex +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Le Iscrizioni reimpiegate [PDF]
, 2007 I manufatti reimpiegati nel frantoio dell'area 22.000, come negli altri impianti produttivi di Uchi Maius, sono numerosi; in particolare i blocchi recanti iscrizioni, dei quali si fornisce un sintetico catalogo in questo studio, sono ...
Ughi, Esmeralda
core
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
El pluralismo motivacional en la especie humana
Papers, 2010 La Teoría de la Elección Racional ha realizado aportaciones decisivas para el estudio de los fenómenos sociales. No obstante, el uso de supuestos falsos o excesivamente incompletos supone un importante lastre en este sentido.
Jordi Tena Sánchez
doaj +1 more source
Stucchi veneziani del Settecento: il caso di palazzo Maffetti [PDF]
, 2014 Using several unpublished 18th and 19th century documents, the author tries reconstructs the cronology of both the construction and the interior decoration of palazzo Maffetti Tiepolo in Venice, rebuilt between 1710 and 1715.
Rössler, Jan-Christoph
core +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Lesiones del cartílago de la rodilla
Archivo Médico de Camagüey, 2013 Fundamento: las lesiones del cartílago de la rodilla producen en los enfermos dolor y pérdida de la capacidad funcional de manera progresiva. El tratamiento de esta enfermedad es difícil, debido a la poca capacidad biológica de los cartílagos para su ...
Alejandro Álvarez López +3 more
doaj