Results 161 to 170 of about 840,716 (345)

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

British Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić, Patrick Eustaquio, Elvira Meni Maria Gkrinia, Ivana Stević, Eugen Javor, Yun Wah Lam, Slobodan Janković, Dinko Vitezić   +7 more
wiley   +1 more source

A Network Proposal for the Caput Adriae in the Middle and Recent Bronze Ages (MBA2 - RBA1)

IpoTESI di Preistoria
Caput Adriae, the territory between Istria and Friuli, experienced a systematic occupation both through the spread of fortified settlements in Istria, Karst and Upper Friuli, and through the emergence of numerous open settlements in the lowlands, between
Giulio Simeoni
doaj   +1 more source

International student agency in academic self‐formation: Mobility as agency situated within knowledge structures

British Educational Research Journal, EarlyView.
Abstract With growing attention to student agency in academic and policy discourse, international education has become a prominent context for examining how students navigate new cultural, academic, linguistic and social environments. However, much of this discussion attributes student agency to the ‘international’ aspect, while overlooking the ...
Soyoung Lee
wiley   +1 more source

The Sea! The Sea! A Rite from the South of Anatolia (CTH 719) [PDF]

, 2015
An edition of a Hittite ritual text from southern Anatolia recovered from the archives of Hattusa (Late Bronze Age)http://deepblue.lib.umich.edu/bitstream/2027.42/110989/1/CTH 719—GsOtten.pdfDescription of CTH 719—GsOtten.pdf : main ...
Beckman, Gary
core  

Disingenuous ‘box‐ticking’: Undergraduate students' attitudes towards university mental health awareness efforts

British Educational Research Journal, EarlyView.
Abstract Mental health problems are common among UK undergraduate students. In response, many universities have put considerable effort into raising awareness about student mental health problems and avenues of support (e.g., via workshops, posters, email newsletters and social media posts).
Sorcha Finan, Lucy Foulkes
wiley   +1 more source

A pipeline crisis or a sustainability crisis? Local and national succession planning for headteachers in England

British Educational Research Journal, EarlyView.
Abstract Recruiting and retaining school leaders is a challenge in many systems worldwide. Previous research has identified three distinct ways in which succession planning can be conceptualised and approached: a ‘pipeline’ approach seeks to match supply and demand for the posts that need filling; a ‘pool’ strategy involves proactively identifying and ...
Toby Greany, Pat Thomson, Tom Perry, Mike Collins   +3 more
wiley   +1 more source

RBD‐SD1 Nanoparticle Vaccines From DPP4‐Using Merbecoviruses Elicit a Cross‐Reactive Antibody Response but Limited Cross‐Protective Immunity

Biotechnology and Bioengineering, EarlyView.
SpyCatcher‐mi3 nanoparticles displaying RBD‐SD1 from MERS‐CoV, NL140422, and HKU4 elicited robust and cross‐reactive IgG responses in mice. Only MERS‐CoV RBD‐SD1 induced neutralizing antibodies against MERS‐CoV and protected human DPP4 mice from a MERS‐CoV challenge, indicating conserved serologic but limited cross‐neutralizing epitopes.
Peter J. Halfmann, Jeong Soo Lee, Tong Wang, Augustine Duffy, Janie E. Rogers, Natasha Chen, Elizabeth Frimpong, Carmen Rai, Yoshihiro Kawaoka, Ravi S. Kane   +9 more
wiley   +1 more source

Progress in all‐dry‐processed inorganic perovskite solar cells

Bulletin of the Korean Chemical Society, EarlyView.
This review summarizes recent advances in all‐inorganic perovskite solar cells, focusing on vacuum‐based deposition strategies for Cs‐based inorganic perovskite absorbers and inorganic charge transporting materials. We highlight the key principles governing inorganic film growth and future directions toward high‐performance all‐dry‐processed inorganic ...
Yo‐Han Jeon, Jae‐Hwan Kim, Jin‐Wook Lee   +2 more
wiley   +1 more source

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source

Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

BMEMat, EarlyView.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang, Xueyin Hu, Wei Cheng, Lumeng Zhang, Yuanfang Chen, Qinrui Fu, Luntao Liu, Saijun Fan   +7 more
wiley   +1 more source