Results 211 to 220 of about 1,797,826 (252)

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Long Noncoding RNA PCALRx Interacts with Pyruvate Carboxylase to Drive Multi‐Organ Developmental Toxicity in Zebrafish Embryos Exposed to Amoxicillin

Advanced Science, EarlyView.
Embryonic amoxicillin exposure disrupts multi‐organ development in zebrafish larvae through a lncRNA–metabolic enzyme regulatory axis. PCALRx associates with pyruvate carboxylase, promotes PC protein ubiquitination, and impairs mitochondrial energy metabolism, while vitamin B1 partially restores PC‐centered metabolic function and developmental outcomes.
Yixue Yao, Ping Jiang, Xinli Zhou, Mengying Yin, Qiong Luo, Hui Wang   +5 more
wiley   +1 more source

Toward Personalized Theranostics: A Modular PET Platform for Antibody‐Based Imaging and Therapy

Advanced Science, EarlyView.
This modular, site‐specific antibody platform enables customizable conjugates for PET imaging and therapy. Interchangeable payloads – including radiometals, cytotoxics, and fluorophores – support adaptable, multimodal applications with limited off‐target effects. In vivo, the DFO/DOTAGA bischelate immunoconjugate provided clear tumor delineation in PET/
Delphine Vivier, Megane Grah Kple, Julen Ariztia, Marion Leroux, Mathieu Moreau, Michael Claron, Maxime Cheveau, Adam Laouafa, Agnieszka Kownacka, Camille Petitot, John Simonet, Alexandre M. M. Dias, Sophie Poty, Charles Truillet, Bertrand Collin, Alexandra Oudot, Franck Denat   +16 more
wiley   +1 more source

Late Pleniglacial and Late Glacial aeolian phases in The Netherlands

, 1999
openaire   +1 more source

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Last Glacial Maximum, Late Glacial and Holocene of Patagonia

2022
Fil: Coronato, Andrea Maria Josefa. Consejo Nacional de Investigaciones Científicas y Técnicas.
Rabassa, Jorge Oscar, Coronato, Andrea Maria Josefa, Martínez, Oscar Alfredo, Reato, Agustina   +3 more
openaire   +2 more sources

The late proterozoic glacial era

Palaeogeography, Palaeoclimatology, Palaeoecology, 1985
Abstract The Late Proterozoic glacial record is reviewed on a global basis as a setting and introduction for that part of the symposium concerned with West African tillites. No unequivocal glacial deposits have yet been recorded in the interval 1.0–2.0 Ga.
M.J. Hambrey, W.B. Harland
openaire   +1 more source

Late-glacial and early post-glacial Scotland

Proceedings of the Society of Antiquaries of Scotland, 1937
  
openaire   +1 more source

Glacial and Late Glacial Processes in Western Iceland

Geografiska Annaler: Series A, Physical Geography, 1975
The presence of glacial marine drift, a hybrid deposit containing sub-fossil shells of age about 12,000 years B.P.
openaire   +1 more source

A note on the glacial and late glacial history of caithness

Geological Journal, 1981
AbstractIt is generally accepted that in the last glaciation Scottish ice from the Moray Firth flowed to the northwest across Caithness depositing shelly drift. Examination of striae along the east coast of Caithness shows that some were formed by ice flowing into and not out of the Moray Firth.
openaire   +1 more source

Late glacial and post‐glacial shorelines in north‐east Antrim

Irish Geography, 1965
Abstract not available...
openaire   +1 more source