Results 71 to 80 of about 20,544 (264)

Two Circumpolar Ground Beetle Species (Coleoptera: Carabidae) Were in Hokkaido, Japan, Late in the Last Glacial Period

Quaternary
Fossilized body parts of two cold-adapted ground beetle species, Elaphrus lapponicus and Diacheila polita, were identified from a deposit dated to the Late Glacial period in Hokkaido, Japan.
Shigehiko Shiyake
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Dual ancestries and ecologies of the Late Glacial Palaeolithic in Britain. [PDF]

Nat Ecol Evol, 2022
Charlton S, Brace S, Hajdinjak M, Kearney R, Booth T, Reade H, Tripp JA, Sayle KL, Grimm SB, Bello SM, Walker EA, Gilardet A, East P, Glocke I, Larson G, Higham T, Stringer C, Skoglund P, Barnes I, Stevens RE.   +19 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

The deglaciation of the mountains of Mexico and Central America

Cuadernos de Investigación Geográfica, 2017
The last deglaciation is an interval of marked changes in the climate system. The records of glaciation of tropical mountains offer unique opportunities to assess the timing of changes and the sensitivity of tropical climates to global and regional ...
L. Vázquez-Selem, M.S. Lachniet
doaj   +1 more source

Summer paleohydrology during the Late Glacial and Early Holocene based on δ²H and δ¹⁸O from Bichlersee, Bavaria. [PDF]

Sci Rep, 2023
Prochnow M, Strobel P, Bliedtner M, Struck J, Bittner L, Szidat S, Salazar G, Schneider H, Acharya S, Zech M, Zech R.   +10 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Application data base paleogeographic Kola peninsula «Q-KOLA» in paleolimnological research

Transactions of the Karelian Research Centre of the Russian Academy of Sciences, 2015
The paleogeographic database “Q-KOLA” was created to systematize, statistically analyze and visualize information about the history of the natural ecosystems of the Kola Peninsula in the Late Glacial and Holocene. The database can be used in limnological
Ivan Grekov, Dmitry Subetto
doaj   +1 more source

A Continuous Centennial Late Glacial-Early Holocene (15-10 cal kyr BP) Palynological Record from the Iberian Pyrenees and Regional Comparisons. [PDF]

Plants (Basel), 2023
Rull V, Blasco A, Calero MÁ, Blaauw M, Vegas-Vilarrúbia T.   +4 more
europepmc   +1 more source