Results 141 to 150 of about 1,748,641 (295)

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

open access: yesAdvanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou   +6 more
wiley   +1 more source

Unique Role of Microstructure of a Bioimplant Zinc Alloy and Protein Content of Simulated Body Fluid in Corrosion and Fracture

open access: yesAdvanced Functional Materials, EarlyView.
BSA addition to physiological solutions enhances resistance of a Zn alloy to stress corrosion cracking (SCC) but reduces its corrosion resistance. Extended surface characterization explains the contrasting influences on corrosion and SCC. Unexpectedly, the alloy suffers transgranular SCC (TGSCC), despite extensive grain boundary precipitation. Thorough
RK Singh Raman   +9 more
wiley   +1 more source

Vegetation and environmental dynamics in the Páramo of Jimbura region in the southeastern Ecuadorian Andes during the late Quaternary.

open access: yes, 2012
The last 15,000 years of vegetation, fire and climate history were reconstructed from the Laguna Natosa Peat bog core (3600 m elevation) in the Páramo of Jimbura region in the Cordillera Real, close to the Peruvian border of southern Ecuador in the ...
León Yánez, Susana Del Consuelo
core   +1 more source

Investigation of the Geological, Mineralogical, and Geochemical Contents of the Sedimentary Fills in the Northern Area of the Quaternary-Aged Bor Basin (Niğde/Turkey): Implications for Sediment Source and Paleoclimates

open access: yesQuaternary
In the northern part of the Niğde (Central Anatolian) Quaternary Bor Basin, stratigraphic sections P1 and P2 were sampled, reaching depths of 11 m and 25 m.
Alperen Sahinoglu, Ali Gürel
doaj   +1 more source

Engineering a Fluorinated AlPO4 Interface: Toward High Initial Coulombic Efficiency and Stable Oxygen Redox in Li‐Rich Layered Oxide Cathodes

open access: yesAdvanced Functional Materials, EarlyView.
We report a chemically incorporated fluorinated AlPO4 (AlPO4‐F) architecture that functions as a multifunctional “interfacial fortress” for Li‐rich layered oxides (LLOs). By modulating the surface potential to –32.16 mV, this architecture enriches Li+ concentration and repels detrimental electrolyte anions.
Hojun Moon   +13 more
wiley   +1 more source

Glacial-interglacial atmospheric CO2 change: a possible "standing volume" effect on deep-ocean carbon sequestration [PDF]

open access: yes
So far, the exploration of possible mechanisms for glacial atmospheric CO2 drawdown and marine carbon sequestration has tended to focus on dynamic or kinetic processes (i.e. variable mixing-, equilibration- or export rates).
Skinner, L. C.
core  

LGM and Late Glacial glacier advances in the Cordillera Real and Cochabamba (Bolivia) deduced from 10Be surface exposure dating [PDF]

open access: yesClimate of the Past, 2007
Surface exposure dating (SED) is an innovative tool already being widely applied for moraine dating and for Late Quaternary glacier and climate reconstruction.
H. Veit, P. W. Kubik, Ch. Kull, R. Zech
doaj  

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj   +23 more
wiley   +1 more source

Stratigraphic evidence for modern‐like glacier extents in south‐central Alaska within the last glacial period (MIS 3)

open access: yesBoreas
The last (Wisconsinan) glacial period was punctuated in North America by two glacial maxima, known as the Early and Late Wisconsinan glaciations. In Alaska, these maxima and their subsequent retreats have been the object of dating efforts to reconstruct ...
Bruno Belotti   +5 more
doaj   +1 more source

Patient‐Derived 3D Heart‐On‐a‐Chip Model of Dilated Cardiomyopathy With Embedded Bead‐Based Mapping of Tissue Contractility

open access: yesAdvanced Healthcare Materials, EarlyView.
A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi   +10 more
wiley   +1 more source

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