Results 71 to 80 of about 2,746,446 (292)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Variability of thermocline and intermediate waters in the South Atlantic

, 2011
This thesis investigates the variability of the intermediate and thermocline water mass properties in the South Atlantic, with a particular focus on salinity.
McCarthy, Gerard
core   +1 more source

Growth Curve Models and Clustering Techniques for Studying New Sugarcane Hybrids

AgriEngineering
Sugarcane (Saccharum spp.) is a crop of significant industrial and nutritional value, essential for producing various products. Due to its importance, genetic improvement programs involve a rigorous selection process.
Carlos David Carretillo Moctezuma, María Guzmán Martínez, Flaviano Godínez-Jaimes, José C. García-Preciado, Ramón Reyes Carreto, José Terrones Salgado, Edgar Pérez Arriaga   +6 more
doaj   +1 more source

Gantry-Mounted Linear Accelerator–Based Stereotactic Body Radiation Therapy for Low- and Intermediate-Risk Prostate Cancer

Advances in Radiation Oncology, 2020
Purpose: To establish the safety and efficacy of gantry-mounted linear accelerator-based stereotactic body radiation therapy (SBRT) for low- and intermediate-risk prostate cancer.
Audrey T. Dang, MD, Rebecca G. Levin-Epstein, MD, David Shabsovich, BS, Minsong Cao, PhD, Christopher King, PhD, MD, Fang-I. Chu, PhD, Constantine A. Mantz, MD, Kevin L. Stephans, MD, Chandana A. Reddy, MS, D. Andrew Loblaw, MD, Patrick Cheung, MD, Marta Scorsetti, MD, Luca Cozzi, PhD, Albert S. DeNittis, MD, Yue Wang, MD, Nicholas Zaorsky, MD, Nicholas G. Nickols, MD, PhD, Patrick A. Kupelian, MD, Michael L. Steinberg, MD, Amar U. Kishan, MD   +19 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Enhancement of optical absorption in Ga-chalcopirite-based intermediate-band materials for high efficiency solar cells [PDF]

, 2010
We present absorption properties enhancement for two CuGaS2-based intermediate-band materials, as promising compounds for high efficiency, lower-cost photovoltaic devices.
P. Wahnón, P. Palacios, Palacios Clemente, Pablo, I. Aguilera, Aguilera Bonet, Irene, Wahnón Benarroch, Perla   +5 more
core   +1 more source

Identification of Interleukin1β as an Amplifier of Interferon alpha-induced Antiviral Responses.

PLoS Pathogens, 2020
The induction of an interferon-mediated response is the first line of defense against pathogens such as viruses. Yet, the dynamics and extent of interferon alpha (IFNα)-induced antiviral genes vary remarkably and comprise three expression clusters: early,
Katharina Robichon, Tim Maiwald, Marcel Schilling, Annette Schneider, Joschka Willemsen, Florian Salopiata, Melissa Teusel, Clemens Kreutz, Christian Ehlting, Jun Huang, Sajib Chakraborty, Xiaoyun Huang, Georg Damm, Daniel Seehofer, Philipp A Lang, Johannes G Bode, Marco Binder, Ralf Bartenschlager, Jens Timmer, Ursula Klingmüller   +19 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Akuntansi keuangan = Intermediate accounting

, 2009
Judul Asli Intermediate Accounting. Jilid 2xviii, 858 [40] p.
Stice, James D, Skousen, K. Fred, Stice, James D., Stice, Earl K, Stice, Earl K.   +4 more
core