Results 81 to 90 of about 2,850,086 (292)

Growth Curve Models and Clustering Techniques for Studying New Sugarcane Hybrids

open access: yesAgriEngineering
Sugarcane (Saccharum spp.) is a crop of significant industrial and nutritional value, essential for producing various products. Due to its importance, genetic improvement programs involve a rigorous selection process.
Carlos David Carretillo Moctezuma   +6 more
doaj   +1 more source

Gantry-Mounted Linear Accelerator–Based Stereotactic Body Radiation Therapy for Low- and Intermediate-Risk Prostate Cancer

open access: yesAdvances in Radiation Oncology, 2020
Purpose: To establish the safety and efficacy of gantry-mounted linear accelerator-based stereotactic body radiation therapy (SBRT) for low- and intermediate-risk prostate cancer.
Audrey T. Dang, MD   +19 more
doaj   +1 more source

Osteology and relationships of Rhinopycnodus gabriellae gen. et sp. nov. (Pycnodontiformes) from the marine Late Cretaceous of Lebanon [PDF]

open access: yes, 2013
The osteology of Rhinopycnodus gabriellae gen. and sp. nov., a pycnodontiform fish from the marine Cenomanian (Late Cretaceous) of Lebanon, is studied in detail.
Taverne, Louis   +4 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Identification of Interleukin1β as an Amplifier of Interferon alpha-induced Antiviral Responses.

open access: yesPLoS Pathogens, 2020
The induction of an interferon-mediated response is the first line of defense against pathogens such as viruses. Yet, the dynamics and extent of interferon alpha (IFNα)-induced antiviral genes vary remarkably and comprise three expression clusters: early,
Katharina Robichon   +19 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

MYRACRODRUON URUNDEUVA FR ALL. (AROEIRA TREE) POPULATION DYNAMICS, DIAMETER GROWTH RATE AND ITS POTENTIAL FOR SUSTAINABLE MANAGEMENT IN SUCCESSIONAL TROPICAL DRY FORESTS OF BRAZIL

open access: yesRevista Árvore, 2018
Myracrodruon urundeuva, better known in Brazil as “Aroeira”, is an arboreal species highly used for its commercial and pharmacological value. Despite the high commercial value in the timber market, this species lacks studies analyzing the recovery time ...
Sofia Calvo Rodriguez   +3 more
doaj   +1 more source

Evaluation of Early and Late/Intermediate Maize Varieties for Grain Yield Potential and Adaptation to a Southern Guinea Savanna Agro-ecology of Nigeria [PDF]

open access: yes, 2012
Drought-tolerant maize varieties belonging to two different maturity (10 early and 10 late/intermediate) groups were evaluated for yield and other related characters in the southern Guinea savanna (SGS) of Nigeria for two years (2009 and 2010).
Mahamood, J.   +6 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

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