Results 21 to 30 of about 325,562 (254)
Clocks & Sleep, 2021 Chronotype reflects circadian timing and can be determined from biological markers (e.g., dim light melatonin onset; DLMO), or questionnaires (e.g., Morningness-Eveningness Questionnaire; MEQ, or Munich Chronotype Questionnaire; MCTQ).
Andrew M. Reiter +2 more
doaj +1 more source
BMC Psychiatry, 2023 Background Clozapine is the only antipsychotic medication with proven efficacy against treatment-resistant schizophrenia. This multicenter retrospective cohort study aimed to evaluate the impact of a delay in clozapine initiation on long-term outcomes ...
Masakazu Hatano +9 more
doaj +1 more source
Observing a late folding intermediate of Ubiquitin at atomic resolution by NMR [PDF]
Protein Science, 2016 AbstractThe study of intermediates in the protein folding pathway provides a wealth of information about the energy landscape. The intermediates also frequently initiate pathogenic fibril formations. While observing the intermediates is difficult due to their transient nature, extreme conditions can partially unfold the proteins and provide a glimpse ...
Parag Surana, Ranabir Das
openaire +2 more sources
Photocatalytic Late-Stage Functionalization of Sulfonamides via Sulfonyl Radical Intermediates
ACS Catalysis, 2022 A plethora of drug molecules and agrochemicals contain the sulfonamide functional group. However, sulfonamides are seldom viewed as synthetically useful functional groups. To confront this limitation, a late-stage functionalization strategy is described, which allows sulfonamides to be converted to pivotal sulfonyl radical intermediates.
Tilby, M +5 more
openaire +4 more sources
Oromandibular Dyskinesia as the Initial Manifestation of Late-Onset Huntington Disease [PDF]
Journal of Movement Disorders, 2011 Huntington’s disease (HD) is a neurodegenerative disorder characterized by a triad of choreoathetosis, dementia and dominant inheritance. The cause of HD is an expansion of CAG trinucleotide repeats in the HD gene.
Dong-Seok Oh +5 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan +3 more
wiley +1 more source
Accurate Spectroscopy of Intermediate and Late Spectral Types [PDF]
Symposium - International Astronomical Union, 1988 Elemental abundances in the Sun and in meteorites are examined with respect to their qualification as a standard ofpopulation I composition. Some problems that arise in connection with spectroscopic determinations of abundances in the Sun, and in other late-type stars, are discussed with emphasis onphotospheric modelsanddepartures from LTE.
openaire +1 more source
Micronutrient Accumulation in Conilon Coffee Berries with Different Maturation Cycles
Revista Brasileira de Ciência do Solo, 2015 The number of days between anthesis and maturation of conilon coffee berries varies according to the genotype. Thus, it is believed that periods of greater nutrient demand for fruit formation also vary according to the genotype, directly influencing ...
Wellington Braida Marré +5 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families (“Standards”) are evidence‐based guidelines for psychosocial care in pediatric oncology. Care related to the three “Asking and Monitoring” Standards—Assessment of Psychosocial Needs, Assessment of Financial Needs, and Monitoring Neurocognitive Problems ...
Julia B. Tager +8 more
wiley +1 more source
The star formation history of intermediate-redshift late-type galaxies [PDF]
Monthly Notices of the Royal Astronomical Society, 2004 We combine the latest observations of disk galaxy photometry and rotation curves at moderate redshift from the FORS Deep Field (FDF) with simple models of chemical enrichment. Our method describes the buildup of the stellar component through infall of gas and allows for gas and metal outflows.
Ferreras, Ignacio +3 more
openaire +4 more sources