Safety and efficacy of an extended macular vision intraocular lens (IOL) for age-related macular degeneration (AMD) in real-world settings. [PDF]
BMC OphthalmolHengerer FH +6 more
europepmc +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
GUÁNUCOS OCCUPATION FROM MIDDLE HORIZON PERIOD TO LATE INTERMEDIATE
, 2012 El Alto Marañón fue testigo de varios grupos culturales que tuvieron una prolongada ocupación. Aquí se aborda sobre uno de ellos, los Guánuco, que han sido objeto de análisis por los historiadores y confundidos como parte de un presunto Imperio Yarowilca y que ha conllevado a errores de percepción de lo que fueron en realidad, una nación con diferentes
openaire +1 more source
Associations between chronotype, physical activity and cognition in a free-living setting. [PDF]
Exp Brain ResHolt E +6 more
europepmc +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Multimodal graph neural networks in healthcare: a review of fusion strategies across biomedical domains. [PDF]
Front Artif IntellVaida M, Huang Z.
europepmc +1 more source
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Field Susceptibility of Almond (Prunus dulcis) Cultivars to Red Leaf Blotch Caused by Polystigma amygdalinum in Apulia (Italy) and Influence of Environmental Conditions. [PDF]
Plants (Basel)Lucchese PG +12 more
europepmc +1 more source
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
FEBS Open Bio, EarlyView.Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source