Results 161 to 170 of about 340,011 (295)

Structures of folding intermediates on BAM show diverse substrates fold by a conserved mechanism. [PDF]

open access: yesProc Natl Acad Sci U S A
Thomson BD   +5 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Late Holocene mud sedimentation and diagenesis in the Firth of Thames: Bentonites in the making

open access: yes, 2013
Late Holocene mud sedimentation in the southern Firth of Thames has been described from analysis of a number of shallow marine sediment cores. Three distinct lithofacies are distinguished on the basis of sediment texture and mineralogy.
Naish, Timothy R.
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Lineage tracing reveals photoreceptor precursor cell subpopulations that contribute to murine retinogenesis. [PDF]

open access: yesFront Cell Dev Biol
Yano JJ   +5 more
europepmc   +1 more source

The taxonomy and taphonomy in mio-pliocene and late middle pleistocene micromammals from the Cape west coast, South Africa

open access: yes, 2004
Includes bibliographical references.The study sites investigated in this thesis are situated along the southwest coast of South Africa in an area dominated by the sclerophyllous fynbos of the Strandveld and Sandveld, which supports a well-known ...
Matthews, Thalassa
core  

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