Results 51 to 60 of about 321,360 (252)

La cerámica de Coscopunta, un sitio del Periodo Intermedio Tardío en la provincia de Carhuaz, Callejón de Huaylas, Perú

Bulletin de l'Institut Français d'Études Andines, 2015
This essay describes a large group of complete or nearly complete Late Intermediate Period pottery vessels uncovered by a farmer in 1979 at the site of Coscopunta, near the town of the Anta, Carhuaz Province, Ancash.
Richard L. Burger, Lucy C. Salazar
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

OSTEOFITOSIS VERTEBRAL EN POBLACIONES PREHISPÁNICAS DE SAN PEDRO DE ATACAMA, NORTE DE CHILE

Estudios Atacameños
Se estudió la osteofitosis vertebral como indicador de estrés físico en grupos humanos prehistóricos de San Pedro de Atacama, durante los períodos Medio (400 DC - 1000 DC) e Intermedio Tardío (1000 DC - 1450 DC).
Rocío López-Barrales, Mark Hubbe, Eugenio Aspillaga, Walter A Neves, Hermann M Niemeyer   +4 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Growth Curve Models and Clustering Techniques for Studying New Sugarcane Hybrids

AgriEngineering
Sugarcane (Saccharum spp.) is a crop of significant industrial and nutritional value, essential for producing various products. Due to its importance, genetic improvement programs involve a rigorous selection process.
Carlos David Carretillo Moctezuma, María Guzmán Martínez, Flaviano Godínez-Jaimes, José C. García-Preciado, Ramón Reyes Carreto, José Terrones Salgado, Edgar Pérez Arriaga   +6 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Gantry-Mounted Linear Accelerator–Based Stereotactic Body Radiation Therapy for Low- and Intermediate-Risk Prostate Cancer

Advances in Radiation Oncology, 2020
Purpose: To establish the safety and efficacy of gantry-mounted linear accelerator-based stereotactic body radiation therapy (SBRT) for low- and intermediate-risk prostate cancer.
Audrey T. Dang, MD, Rebecca G. Levin-Epstein, MD, David Shabsovich, BS, Minsong Cao, PhD, Christopher King, PhD, MD, Fang-I. Chu, PhD, Constantine A. Mantz, MD, Kevin L. Stephans, MD, Chandana A. Reddy, MS, D. Andrew Loblaw, MD, Patrick Cheung, MD, Marta Scorsetti, MD, Luca Cozzi, PhD, Albert S. DeNittis, MD, Yue Wang, MD, Nicholas Zaorsky, MD, Nicholas G. Nickols, MD, PhD, Patrick A. Kupelian, MD, Michael L. Steinberg, MD, Amar U. Kishan, MD   +19 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source