Results 101 to 110 of about 7,616,557 (295)

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Cambios y continuidades en el valle de Lurín a la llegada de los incas: el caso de Pampa de Flores

open access: yesBulletin de l'Institut Français d'Études Andines, 2017
This research explores the continuity, transformation and changes that occurred in the Late Intermediate Period monumental architecture of the Lurin Valley with the arrival of the Incas, and the consequences that had on its social and political ...
Camila Capriata Estrada   +1 more
doaj   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

The holders of the title 'Servant of Neith' in the Late Period

open access: yes
The article deals with the priestly title ḥm nt, “servant of Neith”, during the Late Period. Although al- ready known at the beginning of the dynastic period, the title became relatively common from the Third Intermediate Period onwards, particularly in
Marco Zecchi
core   +1 more source

El fenómeno “pucara” visto desde la puna jujeña

open access: yesEstudios Atacameños, 1997
En los Andes Centro Sur el uso del término pucara es ambiguo, dado que se lo utiliza para denominar tanto fortalezas, poblados fortificados, asentamientos naturalmente inexpugnables o sitios estratégicos que controlan recursos o vías de circulación ...
Marta Ruiz, María Ester Albeck
doaj   +1 more source

Late Second Intermediate Period to Early New Kingdom [PDF]

open access: yes, 2013
The main events of the transition period from the Second Intermediate Period to the New Kingdom are the expulsion of the Hyksos, the reunification of the country, and the reestablishment of a Nubian province. During, and following this process of reunification, the Ahmosids reorganized the administration and started restoration projects.
openaire  

Intermediate Inflation or Late Time Acceleration? [PDF]

open access: yes, 2008
The expansion rate of “intermediate inflation” lies between the exponential and power law expansion but corresponding accelerated expansion does not start at the onset of cosmological evolution.
Abhik Kumar Sanyal
core   +1 more source

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

open access: yesMolecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis   +20 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Global averaged temperature anomaly in the intermediate period, hot period, and the percentage of warming that has occurred by the intermediate period.

open access: yes
Global averaged temperature anomaly in the intermediate period, hot period, and the percentage of warming that has occurred by the intermediate period.
Akshaya Nikumbh (17889086)   +6 more
core   +1 more source

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