Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review
ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley +1 more source
Parkinson Disease Subtype Stability and Eventual Convergence
ABSTRACT Objective Previous research identified distinct Parkinson disease (PD) clinical subtypes of “Motor Only,” “Psychiatric & Motor,” and “Cognitive & Motor” based on comprehensive, multidomain classification. Whether these subtypes reflect distinct trajectories or progressive disease stages remains unknown.
Laura M. Rosok +10 more
wiley +1 more source
Carbon-Ion Radiation Therapy for Unresectable Solitary Fibrous Tumor of the Intermediate Category: A Nationwide Multi-institutional Observational Study by the Japan Carbon-Ion Radiation Oncology Study Group. [PDF]
Tsuchida K +12 more
europepmc +1 more source
Timing of First Acute Rejection and Long-Term Kidney Allograft Survival in the Contemporary Calcineurin-Inhibitor Era: A Single-Center Cohort Study (2000-2018). [PDF]
Lee J, Son S, Ju M.
europepmc +1 more source
The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo +9 more
wiley +1 more source
Post-Pubertal Deepbite Changes in Patients With or Without Previous Early Interceptive Treatment: A Retrospective Observational Study. [PDF]
Lomonaco I +4 more
europepmc +1 more source
Objective Gastrointestinal (GI) involvement can lead to malnutrition in patients with systemic sclerosis (SSc). Body mass index (BMI) remains the most widely used marker to screen nutritional status. We aimed to identify predictors of lower BMI in patients with SSc. Methods Patients with SSc from a prospective US cohort meeting 2013 American College of
Ali Y. Ayla +8 more
wiley +1 more source
Bioinformatic Analysis and Tissue-Specific Expression of Clock Genes and <i>Opn5</i> in the Chinese Giant Salamander (<i>Andrias davidianus</i>) Under Different Light Conditions. [PDF]
Chen B +6 more
europepmc +1 more source
Objective Youth who experience a sport‐related knee injury have elevated odds of becoming overweight or developing obesity in 3 to 10 years, compounding their risk for posttraumatic osteoarthritis (PTOA). To inform prevention strategies, this study compared patterns of adiposity change between youth with a sport‐related knee injury and uninjured youth ...
Justin M. Losciale +6 more
wiley +1 more source
Direct healthcare burden and costs of operatively managed prosthetic joint infection in a public hospital setting. [PDF]
Condon M +3 more
europepmc +1 more source

