Results 41 to 50 of about 163,382 (255)
Una edad del bronce en los Andes CentralesContribución a la elaboración de una historia ambiental
Bulletin de l'Institut Français d'Études Andines, 2004 Evidence exists of a spectacular territorial development at the beginning of the Late Intermediate Period in the valleys of Piura, Chira and Tumbes: expansion of the agricultural frontier in the equatorial dry forest, changes in the administrative and ...
Anne Marie Hocquenghem
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
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Micronutrient Accumulation in Conilon Coffee Berries with Different Maturation Cycles
Revista Brasileira de Ciência do Solo, 2015 The number of days between anthesis and maturation of conilon coffee berries varies according to the genotype. Thus, it is believed that periods of greater nutrient demand for fruit formation also vary according to the genotype, directly influencing ...
Wellington Braida Marré +5 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
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Tropical Grasslands-Forrajes Tropicales, 2020 Height and mowing of a sward in late winter can change its structure during the subsequent spring and summer seasons, which influences plant growth and animal performance.
Manoel E.R. Santos +5 more
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
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Bulletin de l'Institut Français d'Études AndinesThe precordillera of Tacna, between the communities of Sitajara and Tarata, has long had the reputation of being a zone of cohabitation between local, altiplano and coastal populations.
Romuald Housse
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
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Characteristics of rainfall and erosion under natural conditions of land use in semiarid regions
Revista Brasileira de Engenharia Agrícola e Ambiental, 2013 The characteristics of rainfall can provide important information for management and land use may also minimize the water erosion problems. This study was carried out to evaluate soil and water loss in erosion plots with different coverage, and the ...
Cleene A. de Lima +4 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
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