Results 71 to 80 of about 7,797,572 (314)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

RELACIONES CERÁMICAS Y SOCIALES ENTRE SAN PEDRO DE ATACAMA Y EL LOA SUPERIOR DURANTE EL PERÍODO INTERMEDIO TARDÍO A TRAVÉS DEL ANÁLISIS DE FLUORESCENCIA DE RAYOS X PORTÁTIL

Estudios Atacameños
Durante el período Intermedio Tardío las comunidades de San Pedro de Atacama y del Loa Superior produjeron tipos cerámicos similares. La cerámica, junto a otros materiales, sugieren una intensificación de una identidad regional compartida durante este ...
Emily Stovel, William Whitehead, Michael Deibel, Mauricio Uribe   +3 more
doaj   +1 more source

Intensity modulated radiotherapy (IMRT) or conformational radiotherapy (3D-CRT) with conventional fractionation for prostate cancer: Is there any clinical difference? [PDF]

International Brazilian Journal of Urology
Purpose: To compare the treatment outcomes of a cohort of prostate cancer patients treated with conventional schedule using IMRT or 3DRT technique.
Gustavo Viani, Ana Carolina Hamamura, Alexandre C. Faustino   +2 more
doaj   +2 more sources

Early recurrence during the blanking period and left atrial reverse remodeling after catheter ablation for non-paroxysmal atrial fibrillation

International Journal of Cardiology: Heart & Vasculature, 2020
Background: Early recurrence of atrial tachyarrhythmia (ERAT) during a 90-day blanking period (BP) often occurs after atrial fibrillation (AF) ablation. Left atrial reverse remodeling (LARR), which is the reduction in LA volume (LAV), also occurs during ...
Takafumi Oka, Yasushi Koyama, Koji Tanaka, Yuko Hirao, Nobuaki Tanaka, Masato Okada, Issei Yoshimoto, Ryo Kitagaki, Atsunori Okamura, Katsuomi Iwakura, Yasushi Sakata, Kenshi Fujii, Koichi Inoue   +12 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Acerca de complejidad, desigualdad social y el complejo cultural Pica-Tarapacá en los Andes Centro-Sur (1000-1450 DC)

Estudios Atacameños
El propósito principal de este trabajo es revisar los conceptos de complejidad y desigualdad social, intentando comprender arqueológicamente los sistemas que desarrollaron las poblaciones de los Andes Centro-Sur durante el Período Intermedio Tardío, en ...
Mauricio Uribe R
doaj   +1 more source

MYRACRODRUON URUNDEUVA FR ALL. (AROEIRA TREE) POPULATION DYNAMICS, DIAMETER GROWTH RATE AND ITS POTENTIAL FOR SUSTAINABLE MANAGEMENT IN SUCCESSIONAL TROPICAL DRY FORESTS OF BRAZIL

Revista Árvore, 2018
Myracrodruon urundeuva, better known in Brazil as “Aroeira”, is an arboreal species highly used for its commercial and pharmacological value. Despite the high commercial value in the timber market, this species lacks studies analyzing the recovery time ...
Sofia Calvo Rodriguez, Julio Calvo Alvarado, Mario Marcos do Espírito-Santo, Yule Roberta Ferreira Nunes   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Patrón de asentamiento y uso del espacio. Precordillera de Arica, extremo norte de Chile, siglos X-XV

Bulletin de l'Institut Français d'Études Andines, 2005
On the basis of the survey and analysis of a set of about of thirty archaeological sites, an approach is offered to the settlements patterns existing in the premountain range of Arica, northern Chile during centuries X to the XV.
Juan Chacama R.
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source