Results 51 to 60 of about 7,197,050 (291)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Coexistence, contacts and conflicts in the precordillera of Tacna during the Late Intermediate Period (AD 1100-1450)

open access: yesBulletin de l'Institut Français d'Études Andines
The precordillera of Tacna, between the communities of Sitajara and Tarata, has long had the reputation of being a zone of cohabitation between local, altiplano and coastal populations.
Romuald Housse
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Characteristics of rainfall and erosion under natural conditions of land use in semiarid regions

open access: yesRevista Brasileira de Engenharia Agrícola e Ambiental, 2013
The characteristics of rainfall can provide important information for management and land use may also minimize the water erosion problems. This study was carried out to evaluate soil and water loss in erosion plots with different coverage, and the ...
Cleene A. de Lima   +4 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

RELACIONES CERÁMICAS Y SOCIALES ENTRE SAN PEDRO DE ATACAMA Y EL LOA SUPERIOR DURANTE EL PERÍODO INTERMEDIO TARDÍO A TRAVÉS DEL ANÁLISIS DE FLUORESCENCIA DE RAYOS X PORTÁTIL

open access: yesEstudios Atacameños
Durante el período Intermedio Tardío las comunidades de San Pedro de Atacama y del Loa Superior produjeron tipos cerámicos similares. La cerámica, junto a otros materiales, sugieren una intensificación de una identidad regional compartida durante este ...
Emily Stovel   +3 more
doaj   +1 more source

Intensity modulated radiotherapy (IMRT) or conformational radiotherapy (3D-CRT) with conventional fractionation for prostate cancer: Is there any clinical difference? [PDF]

open access: yesInternational Brazilian Journal of Urology
Purpose: To compare the treatment outcomes of a cohort of prostate cancer patients treated with conventional schedule using IMRT or 3DRT technique.
Gustavo Viani   +2 more
doaj   +2 more sources

Early recurrence during the blanking period and left atrial reverse remodeling after catheter ablation for non-paroxysmal atrial fibrillation

open access: yesInternational Journal of Cardiology: Heart & Vasculature, 2020
Background: Early recurrence of atrial tachyarrhythmia (ERAT) during a 90-day blanking period (BP) often occurs after atrial fibrillation (AF) ablation. Left atrial reverse remodeling (LARR), which is the reduction in LA volume (LAV), also occurs during ...
Takafumi Oka   +12 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Acerca de complejidad, desigualdad social y el complejo cultural Pica-Tarapacá en los Andes Centro-Sur (1000-1450 DC)

open access: yesEstudios Atacameños
El propósito principal de este trabajo es revisar los conceptos de complejidad y desigualdad social, intentando comprender arqueológicamente los sistemas que desarrollaron las poblaciones de los Andes Centro-Sur durante el Período Intermedio Tardío, en ...
Mauricio Uribe R
doaj   +1 more source

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