Results 51 to 60 of about 7,797,572 (314)
The decline of the Tiwanaku state saw the emergence of two new cultures-Pica-Tarapacá and Atacama-during the Late Intermediate Period in northern Chile.
Francisca Santana-Sagredo +3 more
semanticscholar +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Second Intermediate Period [PDF]
In the Second Intermediate Period (late 13th to 17th Dynasty), the territories that had been ruled by the centralized Egyptian state—including Lower Nubia—were divided between the kingdom of Kerma, the Theban kingdom, the kingdom of Avaris, and possibly ...
Ilin-Tomich, Alexander, +1 more
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Edged weapons and knives of the late bronze age southern levant [PDF]
The weaponry of the Late Bronze Age of the Southern Levant has been little-studied in recent decades. This work examines which kinds of edged weaponry and knives were used during the Late Bronze Age in Palestine and Transjordan and sets the whole within ...
Elam, Jenifer Cathran
core
The Tacuil settlement, in the Calchaquí Valleys, presents different types of evidence related to metallurgical activities. This research expands the dataset of previous analyses by including four metal prills and one lump, five copper-bearing minerals ...
Verónica Isabel Williams +5 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
The chronology of the Aegean late bronze age with special reference to the "Minoan” eruption of Thera [PDF]
The chronology of the Aegean Late Bronze Age is a vigorously contested area of archaeological study, with "high" and "low" schemes emerging over the last three decades.
Dunn, Stuart E
core
Intermediate and deep water paleoceanography of the northern North Atlantic over the past 21,000 years [PDF]
Benthic foraminiferal stable isotope records from four high-resolution sediment cores, forming a depth transect between 1237 m and 2303 m on the South Iceland Rise, have been used to reconstruct intermediate and deep water paleoceanographic changes in ...
Thornalley, David. J. R. +2 more
core +1 more source

