Results 151 to 160 of about 78,697 (265)

Glutaminolysis Blockade‐Empowered Bimodal Nanodepot for Spatially Complementary Sono‐Thermal Ablation via PANoptosis and STING Activation Against Large Tumors

open access: yesAdvanced Science, EarlyView.
An injectable bimodal TCPD nanodepot disrupts glutaminolysis and TCA metabolism, sensitizing large tumors to spatially complementary sono‐thermal ablation for complete treatment coverage. This intervention induces mitochondrial and endoplasmic reticulum dysfunction, genotoxicity, and NAD+ depletion, converging to trigger PANoptosome assembly and ...
Yi‐Ming Liu   +10 more
wiley   +1 more source

Sandwich‐Structured Aramid Composite Papers with Heterogeneous Dielectric Layers for Integrated Corona Resistance and Thermal Conductivity

open access: yesAdvanced Science, EarlyView.
A sandwich‐structured aramid composite paper was designed to integrate high corona resistance and thermal conductivity. The fluorinated graphene/aramid surface layers effectively dissipate space charges to suppress corona discharge. Meanwhile, the boron nitride nanotube/aramid core layer constructs continuous heat‐conduction pathways.
Jun‐Wen Ren   +10 more
wiley   +1 more source

Masked Triple-Negative Polycythemia Vera Initially Presenting as Iron Deficiency and Pernicious Anemia. [PDF]

open access: yesCureus
Nedjar OG   +8 more
europepmc   +1 more source

Versatile Microgel Platform for Intervertebral Disc Degeneration Therapy: Targeting Pericyte‐Mediated Fibrosis and Protecting Nucleus Pulposus Cells

open access: yesAdvanced Science, EarlyView.
The engineered MMS@TRP microgel enables targeted, acid‐responsive delivery of a miR‐21 inhibitor to pericytes. It effectively suppresses disc fibrosis by inhibiting TGF‐β signaling while protecting nucleus pulposus cells via sustained, antioxidant tannic acid release.
Fei Ma   +12 more
wiley   +1 more source

A Hybrid Hierarchical Framework for Quantifying Mechanical Markers in Atherosclerotic Disease Progression: A New Approach for Diagnosis and Risk Assessment

open access: yesAdvanced Science, EarlyView.
The mechanobiological basis of atherosclerotic progression and its contribution to spatial and temporal heterogeneity remain incompletely understood. Spatially resolved AFM measurements revealed that plaque formation and distinct regions (cap fibrosis, intimal fibrosis, and lipid‐rich core) exhibit heterogeneous elastic modulus and viscoelastic ...
Yidan Zhou   +13 more
wiley   +1 more source

Osmium Nanoparticle Anchoring on CoFe Layered Double Hydroxides Enables High‐Valent Species Stabilization and Efficient Seawater Oxygen Evolution

open access: yesAdvanced Science, EarlyView.
Osmium nanoparticles anchored on CoFe layered double hydroxide (Os/CoFe LDH) stabilize high‐valent Co/Fe species and modulate the interfacial water configuration via surface engineering. This work presents a facile surface engineering strategy for constructing efficient and durable OER electrocatalysts for alkaline seawater, and expands the ...
Xindong She   +8 more
wiley   +1 more source

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