Results 191 to 200 of about 7,319,940 (283)

Philistia In The Late Iron Age II

, 2010
openaire   +1 more source

Late Iron Age And Roman Pottery Synthesis

Internet Archaeology, 2015
Joyce Compton, Edward Biddulph
openaire   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

Advanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan, Fuming Cao, Junqiang Mao, Pengbin Yin, Licheng Zhang, Jianjun Wang, Peifu Tang   +6 more
wiley   +1 more source

Ancient DNA reveals elite dynastic rule among Iron Age Eurasian Steppe nomads. [PDF]

Sci Adv
Ghalichi A, Seidualy M, Rohrlach AB, Musralina L, Gnecchi-Ruscone G, Hermes T, Khussainova E, Kahbatkyzy N, Bekmanov B, Iksan O, Altynova N, Tuke J, Roughan M, Baitanayev B, Onggaruly A, Mukhtarova G, Toleubayev A, Zhumatayev R, Rysbek B, Samashev Z, Beisenov A, Jeong C, Haak W, Djansugurova L, Krause J, Childebayeva A.   +25 more
europepmc   +1 more source

A Small‐Molecule DEPTAC Rescues Cognitive Deficits by Targeted Dephosphorylation of Pathological Tau

Advanced Science, EarlyView.
TP2 is a fully synthetic small‐molecule dephosphorylation‐targeting chimera that recruits endogenous PP2A‐Bα to Tau, enabling targeted removal of pathological phosphate modifications. In two tauopathy mouse models, systemic TP2 reduces Tau pathology, preserves neuronal and synaptic integrity, improves neuroimmune homeostasis, and rescues cognition ...
Fei Sun, Yang Liu, Qiuzhi Zhou, Qingyuan Hu, Weixia Wang, Yue Xiao, Jingfen Su, Guanting Liu, Miaomiao Sun, Lixia Chen, Hua Li, Ying Yang, Jian‐Zhi Wang   +12 more
wiley   +1 more source

A multihit cascade of late complications after Roux-en-Y gastric bypass leading to refractory malnutrition: a case report. [PDF]

Int J Surg Case Rep
Park JY, Park KB.
europepmc   +1 more source

An Avalanche Effect Nanomodulator Triggers Cascade Ferroptosis/Cuproptosis for Immunosuppressive Microenvironment Remodeling

Advanced Science, EarlyView.
A nanomodulator called L‐Arginine/lificiguat@Copper‐hollow Prussian blue@Calcium phosphate nanoparticles is constructed to launch a self‐amplifying “avalanche effect” in tumor cells. The ensuing cascade, triggered by the acidic tumor microenvironment and near‐infrared light, induces calcium overload, generates a reactive oxygen species and reactive ...
Hongmei Zhou, Caixi Yu, Guilan Xu, Lijuan Liu, Yujia Liang, Yulin Liang, He Ding, Litu Zhang, Piaoping Yang, Chen Wang   +9 more
wiley   +1 more source

Progressive Cerebellar Dysfunction, Pituitary Insufficiency, and Severe Skeletal Fragility in Adult Survivorship of Childhood Multisystem Langerhans Cell Histiocytosis: A Case Report. [PDF]

Clin Case Rep
Alnahar S, Senjab A, Gharib S, Gharib Z, Hadid L.   +4 more
europepmc   +1 more source

Chemical Bond‐Orchestrated Energy Depletion to Augment Lung Cancer Chemo‐Immunotherapy

Advanced Science, EarlyView.
This study grafted dichloroacetic acid (DCA) into perylenediimide (PDI) skeleton via ionic or covalent bond to create novel metabolic agent PDIC‐AC and PDIC‐NAC, explicitly elaborated the underlying energy metabolism and therapeutic mechanism, and developed a promising strategy for energy metabolism‐targeting chemo‐immunotherapy by chemical bond ...
Xuejie Zhao, Yuting Liu, Xiao Huang, Liwen Zhao, Chunli Li, Yongwei Huang   +5 more
wiley   +1 more source

Mesopotamian ancient DNA reveals Iron Age integration of heterogeneous Bronze Age genetic ancestries following resettlement. [PDF]

Genome Biol
Williams MP, Fetner R, Souilmi Y, Bürger U, Sołtysiak A, Richards A, Haak W, Tobler R, Llamas B, Miglus PA, Cooper AJ.   +10 more
europepmc   +1 more source