Results 41 to 50 of about 78,697 (265)

Cultural encounters during the LBII and IAI: Hittites and “Pelesets” in the Amuq (Hatay) Turkey

Asia Anteriore Antica, 2019
The analysis of long-dormant archaeological documentation and recent archaeological discoveries concerning the Amuq region (modern Hatay) have shed new light on the period from the Late Bronze Age II to the Iron Age III, reopened old questions ...
Marina Pucci
doaj   +1 more source

Human-environmental interactions and seismic activity in a Late Bronze to Early Iron Age settlement center in the southeastern Caucasus

Frontiers in Earth Science, 2022
Long-term human-environmental interactions in naturally fragile drylands are a focus of geomorphological and geoarchaeological research. Furthermore, many dryland societies were also affected by seismic activity.
Hans Von Suchodoletz, Giorgi Kirkitadze, Tiiu Koff, Markus L. Fischer, Markus L. Fischer, Rosa M. Poch, Azra Khosravichenar, Birgit Schneider, Bruno Glaser, Susanne Lindauer, Silvan Hoth, Anna Skokan, Levan Navrozashvili, Mikheil Lobjanidze, Mate Akhalaia, Levan Losaberidze, Mikheil Elashvili   +16 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

La richesse des femmes ou comment l’archéologie vient au genre

Les Nouvelles de l’Archéologie, 2015
This article is based on the analysis of the princely graves from Late Bronze Age to La Tene B1 in the north-alpine complex. After an initial phase of reflection on the methodology to rank a corpus covering a millennium, a second step is to ask the ...
Caroline Trémeaud
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

New evidence for the Late Iron Age in the Posočje region, Slovenia [PDF]

Studia Hercynia, 2023
Several archaeological sites from the Late Iron Age have recently been discovered in Posočje, a region along the upper and middle reaches of the River Soča/Isonzo (NW Slovenija, NE fringes of Italy), which compel us to re -examine the Latenisation of the
Boštjan Laharnar
doaj  

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

FEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi, Alain Dolla, Frauke Baymann, Celine Rommevaux, Latifa Elantak, Helene Gaussier, Matthieu Nouailler   +6 more
wiley   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source