Results 171 to 180 of about 1,658,928 (314)

Introgressed Variation in TaMYB7‐A1 Drives Graded Dormancy and Climate‐Adaptive Pre‐Harvest Sprouting Resistance in Wheat

Advanced Science, EarlyView.
TaMYB7‐A1 directly activates TaABI5 to enhance ABA signaling and regulate ABA‐GA homeostasis, enforcing seed dormancy. Its superior allele, derived from wild einkorn introgression, harbors a MITE insertion that elevates expression and two amino acid substitutions that enhance transcriptional activity, collectively generating graded PHS resistance for ...
Hao Wang, Dongzhi Wang, Yafei Guo, Qi Zheng, Min Zhang, James Simmonds, Jian Hou, Xuemei Liu, Xuelei Lin, Xiaomin Bie, Xiansheng Zhang, Xiaohui Li, Yuan Chen, Xueyong Zhang, Cristobal Uauy, Fei Lu, Chengcai Chu, Zhixi Tian, Jun Xiao   +18 more
wiley   +1 more source

Laparoscopic Delivery of a MnO2‐P‐ICG Patch for Photodynamic Therapy and NK Cell‐Driven Immunotherapy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
This study proposes a flexible MnO2‐P‐ICG nanofiber patch for laparoscopic treatment of liver tumors. The patch alleviates tumor hypoxia and induces photodynamic therapy (PDT) triggered immunogenic cell death, thereby activating the cGAS‐STING pathway and, in synergy with pachymaran, promoting NK cell–mediated innate immunity. This synergistic strategy
Jie Lin, Haoqi Pan, Ke Wu, Junjie Nan, Jinyao Dai, Yushun Chang, Hao Shen, Qingxuan Ye, Haowen Lu, Yuxuan Shen, Boqiang Liu, Ming Wu, Jicheng Yu, Xiujun Cai, Dong Cen   +14 more
wiley   +1 more source

L’apport des manuels d’agronomie à la reconnaissance par les archéologues des techniques agricoles des périodes historiques

Archéopages
Jean-Yves Dufour
doaj   +1 more source

Archaeogenetic insights into the demographic history of Late Neanderthals. [PDF]

Proc Natl Acad Sci U S A
Fotiadou CM, Pedersen JB, Rougier H, Roksandic M, Spyrou MA, Nägele K, Reiter E, Bocherens H, Kandel AW, Haidle MN, Streicher TP, Conard NJ, Schilt F, Godinho RM, Uthmeier T, Doyon L, Semal P, Krause J, Barbieri A, Mihailović D, Crevecoeur I, Posth C.   +21 more
europepmc   +1 more source

High‐Throughput Data Generation and Transfer Learning Enabled Microstructure‐Property Integrated Design of Nickel‐Based Powder Metallurgy Superalloy

Advanced Science, EarlyView.
An integrated transfer learning framework integrates CALPHAD simulations, diffusion‐multiple experiments, and literature data to predict long‐term microstructural stability and short‐term mechanical properties of Ni‐based powder metallurgy superalloys. Based on these model predictions, a high‐performance, low‐density alloy, USTB‐PM750, is designed from
Zixin Li, Hongtao Zhang, Zichao Peng, Yuheng Zhang, Qian Lv, Yihuan Cao, Xuqing Wang, Huadong Fu, Jianxin Xie   +8 more
wiley   +1 more source

Dogs were widely distributed across western Eurasia during the Palaeolithic. [PDF]

Nature
Marsh WA, Scarsbrook L, Yüncü E, Hodgson L, Lin AT, De Iorio M, Thalmann O, Thomas MG, Goor M, Bergström A, Noseda A, Amiri S, Biglari F, Borić D, Bougiouri K, Carmagnini A, Giannì M, Higham T, Lebrasseur O, Linderholm A, Mannino MA, Middleton C, Mustafaoğlu G, Perri A, Peters J, Richards M, Sarıtaş Ö, Skoglund P, Stevens RE, Stringer C, Tabbada K, Talbot HM, Van der Sluis LG, Bello SM, Dimitrijevic V, Martin L, Mashkour M, Parfitt SA, Vukovic S, Brace S, Craig OE, Baird D, Charlton S, Larson G, Barnes I, Frantz LAF.   +45 more
europepmc   +1 more source

Mughal glass: Indian glass from the late modern and early colonial period [PDF]

, 2021
openaire   +1 more source

Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology

Advanced Science, EarlyView.
Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu, Fan Wei, Chi Woo Yoon, Qifa Zhou, Yingxiao Wang   +4 more
wiley   +1 more source

Biogeographic history of the Late Pleistocene and Holocene European small hamsters (subfamily Cricetinae). [PDF]

Sci Rep
Bujalska B, Golubiński M, Popović D, Berto C, Conard NJ, Lemanik A, Luzi E, Marković Z, Nadachowski A, Popov V, Horáček I, Baca M.   +11 more
europepmc   +1 more source

Mechanosensitive Piezo1/Osteocalcin/Irisin Axis Protects Against Disuse‐Induced Muscle Atrophy

Advanced Science, EarlyView.
Mechanical unloading suppresses bone Piezo1 expression, which reduces circulating undercarboxylated osteocalcin (unOCN). unOCN reduction subsequently exacerbates IMM‐induced Fndc5/Irisin decrease and drives severe muscle atrophy. Bone Piezo1 activation or exogenous osteocalcin/Irisin ameliorate muscle atrophy, while muscle‐specific Gprc6a or Fndc5 ...
Zhaolu Wang, Xiuying Jiang, Xi Sun, Hao Chen, Jianjun Jin, Xin'e Shi   +5 more
wiley   +1 more source