Results 81 to 90 of about 1,658,928 (314)

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source

1. The Absolute Dynastic State

, 1958
One of the most significant developments of the early modern period was the evolution of the national state from its beginnings in the feudal monarchy of the High and Late Middle Ages.
Bloom, Robert L., Crapster, Basil L., Dunkelberger, Harold L., Glatfelter, Charles H., Mara, Richard T., Richardson, Norman E., Schubart, W. Richard   +6 more
core  

Designed Liquid Crystalline Nanoassemblies From Clinically Validated Polyunsaturated Lipids for Combined Antioxidant, Anti‐Apoptotic, and Neurotrophic Treatments

Advanced Healthcare Materials, EarlyView.
Ionizable lipid nanoparticles target multiple pathological pathways in neurodegeneration. The designed self‐assembled materials undergo a pH‐triggered structural transformation from a cubosome/hexosome coexistence to a hexosome phase, enhancing intracellular delivery of a multi‐target phytochemical formulation. The antioxidant‐loaded pH‐responsive LNPs
Thelma Akanchise, Fucen Luo, Borislav Angelov, Yuru Deng, Angelina Angelova   +4 more
wiley   +1 more source

Oxygen Supply of Islets of Langerhans by Photosynthetically Active Microalgae in Bioprinted Co‐Cultures Maintains Their Function in a Hypoxic Environment

Advanced Healthcare Materials, EarlyView.
This study developed a bioprinted co‐culture system embedding rat pancreatic islets and Scenedesmus sp. microalgae spatially defined in close vicinity. Red light was found optimal to ensure microalgal photosynthesis while maintaining islet viability and functionality. A tailored co‐culture medium supported both cell types.
Finn Dani, Sarah Duin, Ashwini Rahul Akkineni, Susann Lehmann, Barbara Ludwig, Michael Kühl, Michael Gelinsky, Anja Lode   +7 more
wiley   +1 more source

Rise and development of Slavic accentual paradigms [PDF]

, 2010
It appears that the complexity of Slavic historical accentology is prohibitive for most non-specialists in the field. It may therefore be useful to approach the subject from a number of different angles in order to render it more accessible to a wider ...
Kortlandt, Frederik H. H.
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Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Atlantic Water advection versus sea-ice advances in the eastern Fram Strait during the last 9 ka - multiproxy evidence for a two-phase Holocene [PDF]

, 2013
A sediment core from the West Spitsbergen continental margin was studied to reconstruct climate and paleoceanographic variability during the last ~9 ka in the eastern Fram Strait.
Alley, Andrews, Andrews, Andrews, Barber, Bauch, Bauch, Bauch, Bauch, Bauch, Bianchi, Bond, Bond, Came, Carstens, Chapman, Cronin, Darling, Denton, Dickson, Dorothea Bauch, Duplessy, Duplessy, Dyke, Ebbesen, Ellison, Evgeniya Kandiano, Fairbanks, Forwick, Forwick, Funder, Gammelsrød, Gascard, H. Christian Hass, Hald, Hald, Hald, Hall, Hass, Haugan, Healy-Williams, Hopkins, Humlum, Husum, Jennings, Jennings, Jessen, Johannessen, Johannessen, Johannessen, Karcher, Kaufman, Keigwin, Kirstin Werner, Kleiven, Kozdon, Koç, Kucera, Laskar, Lubinski, Manabe, Mann, Marnela, McDermott, Meredith, Moberg, Moritz, Moros, Moros, Müller, Nesje, Overpeck, Pflaumann, Pflaumann, Prange, Quadfasel, Rabe, Rasmussen, Rasmussen, Rasmussen, Rasmussen, Renssen, Risebrobakken, Risebrobakken, Risebrobakken, Robert F. Spielhagen, Robinson, Rohling, Rudels, Saloranta, Sarnthein, Schauer, Schauer, Schlichtholz, Schulz, Schulz, Seidenkrantz, Seppä, Serreze, Serreze, Shackleton, Simstich, Spielhagen, Spielhagen, Stuiver, Svendsen, Vinje, Vinther, Volkmann, Wanner, Wanner, Werner, Williams, Ślubowska, Ślubowska-Woldengen, Ślubowska-Woldengen   +115 more
core   +1 more source

Epidermal Patch Technologies for Integrated Healthcare and Infection Management

Advanced Healthcare Materials, EarlyView.
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang, Atakan Tevlek, Pawel L. Urban, Boaz Mizrahi, Onome Ejeromedoghene, Roshan Deen, Yuanjing Lin, Jagan Mohan Dodda   +7 more
wiley   +1 more source

Bridging a biogeographic 'gap' : microfossil evidence for the quillwort Isoetes on the Cumberland Plain west of Sydney during the early Colonial period [PDF]

, 2013
Fossil spores preserved on historical archaeological sites at Parramatta and Richmond indicate that two or more species of the quillwort genus Isoetes (family Isoetaceae) were growing along rivers on the Cumberland Plain, west of Sydney, during the late ...
Casey, Mary, Macphail, Mike
core  

Linking early geospatial documents, one place at a time: annotation of geographic documents with Recogito [PDF]

, 2015
Recogito is an open source tool for the semi-automatic annotation of place references in maps and texts. It was developed as part of the Pelagios 3 research project, which aims to build up a comprehensive directory of places referred to in early maps and
Barker, Elton, de Soto Cañamares, Pau, Isaksen, Leif, Simon, Rainer   +3 more
core   +3 more sources