Results 91 to 100 of about 2,996,306 (294)

Late-Onset Growing Pains [PDF]

Archives of Sexual Behavior, 2012
As the Archives inches into its fifth decade, it is experiencing some late-onset growing pains. Since I became Editor in 2002, the number of new submissions has risen dramatically (Fig. 1). It began to dawn on me that it was becoming increasingly difficult to keep up with the flow.
openaire   +2 more sources

Late-onset methylmalonic acidemia and homocysteinemia (cblC disease): systematic review.

Introduction Combined methylmalonic acidemia and homocystinuria, cblC type is an inborn error of intracellular cobalamin metabolism and the most common one. The age of onset ranges from prenatal to adult.
Serrano Moreno, Clara, Miguélez, María, Arhip, Loredana, Cuerda Compes, María Cristina, Romero, Inmaculada, Motilla, Marta, Brox-Torrecilla, Noemí   +6 more
core   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Late-onset schizophrenia and very-late-onset schizophrenia-like psychosis: An international consensus

, 2000
Objective: Although schizophrenia is generally regarded as an illness with onset in late adolescence or early adult life, a sizeable minority of patients first become ill in middle or old age.
?, ?, Seeman, M V, Jeste, D V, Howard, R, Rabins, P V   +4 more
core   +5 more sources

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han, Jiachun Pan, Yuehui Hong, Xiaoyuan Fan, Ming Yao, Lixin Zhou, Yicheng Zhu, Feng Feng, Jun Ni   +8 more
wiley   +1 more source

Birth Weight/ Placental Weight Ratios: Does the association differ between early- and late-onset preeclampsia?

Thai Journal of Obstetrics and Gynaecology, 2019
Objective: Early- and late-onset preeclampsia (PE) may differ in pathophysiology and this can be reflected in differences in birth weight/placental weight (BW/Pl) ratios. Therefore, we compared BW/Pl ratios of births with early- and those with late-onset
Podjanee Phadungkiatwattana, Songphol Puttasiri   +1 more
doaj   +1 more source

Successful management of late-onset Streptococcus mitis endophthalmitis

, 2017
Jinmann Chon,1 Moosang Kim2 1Department of Rehabilitation Medicine, Kyung Hee University Hospital, Kyung Hee University School of Medicine, Seoul, 2Department of Ophthalmology, School of Medcine, Kangwon National University, Chuncheon, Korea Abstract ...
Chon J, Kim M
core  

Early-onset vs. late-onset colorectal cancer trends among veterans [PDF]

, 2020
The purpose of this study was to evaluate trends in the incidence and mortality of early-onset CRC (age at diagnosis < 50), vs. late-onset CRC (age at diagnosis = 50).
Chapman, Monalesia, NC DOCKS at The University of North Carolina at Greensboro   +1 more
core  

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source